Fig. 3
From: COL10A1 promotes tumorigenesis by modulating CD276 in pancreatic adenocarcinoma
Knockdown of COL10A1 inhibits the proliferation, invasion, and migration of Panc-1 pancreatic cancer cells. (A) qRT‒PCR results of COL10A1 expression in different experimental groups of Pan-1 cells: the normal control, siRNA negative control (si-NC), si-COL10A1-a, si-COL10A1-b, and si-COL10A1-c groups (*, P<0.05; **, P<0.01). (B) CCK-8 assay results of the si-NC and si-COL10A1-a groups at 6 h, 24 h, 48 h, and 72 h time intervals. (*, P < 0.05; **, P < 0.01). (C) Transwell assay results showed that the si-COL10A1-a group had a weaker invasive ability. Microscopy images. (*, P < 0.05; **, P < 0.01). (D) Scratch wound healing assay results. Images of the si-NC and si-COL10A1-a groups at 0 and 24 h postinjury. Microscopy images. (*, P < 0.05; **, P < 0.01)