Platelet/Albumin ratio and plateletcrit levels are potential new biomarkers for assessing endoscopic inflammatory bowel disease severity

Table 2 Clinical parameters in patients with UC and CD, and HCs.

Parameters	UC (n = 131)	CD (n = 115)	HCs (n = 369)	p
hs-CRP (mg/L)	8.20 (2.20, 25.45)^a	14.80 (6.10, 40.20)^b	0.90 (0.50, 2.20)	< 0.001
ESR (mm/hr)	18.00 (10.00, 33.50)^a	17.00 (7.00, 36.00)^b	7.00 (4.00, 11.00)	< 0.001
Hb (g/L)	12.00 (10.20, 13.40)^a	11.90 (10.40, 13.00)^b	13.70 (12.90, 14.70)	< 0.001
FIB (g/L)	3.81 (3.25, 4.87)^a,c	4.63 (3.37, 5.50)^b	2.71 (2.39, 3.03)	< 0.001
PLT × 10⁹/L	265.00 (211.00, 324.00)^a,c	305.00 (236.00, 394.00)^b	201.50 (167.75, 224.75)	< 0.001
PCT (%)	0.22 (0.18, 0.25)^a	0.24 (0.20, 0.30)^b	0.19 (0.16, 0.20)	< 0.001
ALB (g/L)	35.10 (30.40, 38.90)^a	36.20 (33.10, 40.40)^b	43.65 (41.50, 44.80)	< 0.001
NLR	3.18 (2.04, 5.59)^a	3.17 (2.21, 4.52)^b	1.86 (1.39, 2.44)	< 0.001
PLR	176.07 (121.60, 301.55)^a,c	246.78 (177.09, 364.32)^b	114.37 (91.55, 144.03)	< 0.001
PLT/ALB	7.76 (5.53, 10.06)^a,c	8.64 (6.60, 11.29)^b	4.86 (3.57, 5.25)	< 0.001

^aUC group vs. HC group, p < 0.05; ^bCD group vs. HC group, p < 0.05. ^cUC group vs. CD group, p < 0.05. Data are presented as the median (interquartile range (IQR)). Differences between groups were tested using one-way analysis of variance; p < 0.05 was considered statistically significant
Abbreviations: UC, ulcerative colitis; CD, Crohn’s disease; HCs, healthy controls, hs-CRP, high sensitive C-reactive protein; ESR, erythrocyte sedimentation rate; Hb, hemoglobin; FIB, fibrinogen; PLT, platelet; PCT, plateletcrit; ALB, Albumin; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; PLT/ALB, platelet-to-albumin ratio

ISSN: 1471-230X