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Table 2 Comparison of baseline characteristics in a post-PSM SEER cohort before and after IPTW adjustment

From: Resection of the primary tumor improves the prognosis of gastrointestinal neuroendocrine neoplasms with liver metastases: mutual validation based on SEER database and institutional data

Characteristics

Before IPTW

After IPTW

Without PTR

PTR

P-value

SMD

Without PTR

PTR

P-value

SMD

(N = 90)

(N = 65)

(N = 139.1)

(N = 149.0)

Age

  

0.0684

−0.1607

  

0.611

0.0493

  < 55

34 (37.8%)

35 (53.8%)

  

54.8 (39.4%)

51.0 (34.3%)

  

  > =55

56 (62.2%)

30 (46.2%)

  

84.4 (60.6%)

98.0 (65.7%)

  

Sex

  

0.562

0.0598

  

0.910

0.0163

 Female

40 (44.4%)

25 (38.5%)

  

60.9 (43.8%)

63.3 (42.4%)

  

 Male

50 (55.6%)

40 (61.5%)

  

78.2 (56.2%)

85.8 (57.6%)

  

PTS

  

< 0.001

   

0.579

 

 Stamoch

27 (30.0%)

11 (16.9%)

 

−0.1308

37.9 (27.3)

38.8 (26.1)

 

− 0.0049

 Small intestine

10 (11.1%)

33 (50.8%)

 

0.3966

26.0 (18.7)

43.0 (28.9)

 

0.0913

 Colorectum

53 (58.9%)

21 (32.3%)

 

−0.2658

75.2 (54.1)

67.1 (45.1)

 

−0.0864

Grade

  

< 0.001

   

0.803

 

 Well differentiation G1

17 (18.9%)

14 (21.5%)

 

0.0265

30.1 (21.6)

29.3 (19.7)

 

−0.0207

 Moderate differentiation G2

12 (13.3%)

45 (69.2%)

 

0.559

40.4 (29.0)

57.1 (38.3)

 

0.0947

 Poor differentiation G3

36 (40.0%)

4 (6.2%)

 

−0.3385

41.7 (30.0)

43.7 (29.3)

 

−0.0072

 NEC

25 (27.8%)

2 (3.1%)

 

−0.247

27.0 (19.4)

18.8 (12.6)

 

−0.0667

T

  

0.252

   

0.638

 

 T1

12 (13.3%)

9 (13.8%)

 

0.0051

22.4 (16.1)

15.0 (10.1)

 

−0.0603

 T2

40 (44.4%)

20 (30.8%)

 

−0.1368

54.2 (39.0)

48.1 (32.3)

 

−0.0643

 T3

17 (18.9%)

20 (30.8%)

 

0.1188

27.3 (19.6)

43.9 (29.5)

 

0.0962

 T4

21 (23.3%)

16 (24.6%)

 

0.0128

35.2 (25.3)

42.0 (28.2)

 

0.0284

Primary tumor size

  

< 0.001

−0.3573

  

0.293

 

  < 2

8 (8.9%)

29 (44.6%)

  

21.4 (15.4%)

35.8 (24.0%)

 

−0.087

  > =2

82 (91.1%)

36 (55.4%)

  

117.7 (84.6%)

113.2 (76.0%)

  

Extrahepatic metastases

  

0.0135

−0.1906

  

0.449

−0.0865

 No

59 (65.6%)

55 (84.6%)

  

99.9 (71.8%)

119.9 (80.4%)

  

 Yes

31 (34.4%)

10 (15.4%)

  

39.2 (28.2%)

29.1 (19.6%)

  
  1. PTR primary tumor resection, PTS primary tumor site, NEC neuroendocrine carcinoma, HR hazard ratio, CI confidence interval, SMD standard mean difference, PSM propensity matching analysis, IPTW inverse probability of treatment weighting, SMD Standard Mean Difference