Table 2 Binary logistic regression analysis results of NLR and one-year lack of response to UDCA treatment in PBC patients

Age (years)

0.989 (0.968–1.011)

0.335

0.988 (0.966–1.011)

0.317

0.993 (0.970–1.018)

0.598

1.011(0.969–1.055)

0.606

Sex (male/female)

0.660 (0.314–1.391)

0.275

1.609 (0.749–3.454)

0.223

1.119 (0.495–2.532)

0.787

1.191(0.327–4.348)

0.791

BMI

0.940 (0.864–1.022)

0.144

0.947 (0.868–1.032)

0.211

0.972 (0.891–1.060)

0.520

1.038(0.914–1.180)

0.565

Hypertension

2.714 (0.998–7.385)

0.051

3.704 (1.137–12.062)

0.030

1.860(0.403–8.595)

0.427

Arterial plaque

8.096 (0.891–7.585)

0.063

0.101 (0.010–1.022)

0.052

0.427(0.032–5.732)

0.521

Thyroid disease

0.482 (0.233–0.998)

0.049

2.122 (0.965–4.666)

0.061

20,639(0.869–8.013)

0.087

Jaundice

0.505 (0.258–0.988)

0.046

0.393(0.095–1.618)

0.196

Albumin (g/l)

0.903 (0.865–0.942)

0.000

0.883(0.806–0.967)

0.008

Globulin (g/l)

1.035 (1.000–1.071)

0.047

0.980(0.924–1.039)

0.489

Total bile acid (u/mol/L)

1.003 (1.001–1.005)

0.005

1.001(0.995–1.007)

0.759

Total bilirubin (umol/L)

1.003 (0.999–1.007)

0.129

0.986(0.972–1.001)

0.060

Alkaline phosphatase (u/l)

1.011 (1.008–1.014)

0.000

1.013(1.009–1.018)

< 0.001

γ-Glutamyl transferase (u/l)

1.003 (1.002–1.004)

0.000

0.999(0.997–1.001)

0.212

HDL-C (mmol/l)

1.313 (0.851–2.025)

0.218

1.346(0.403–4.488)

0.629

LDL-C (mmol/L)

1.325 (1.110–1.582)

0.002

0.531(0.232–1.215)

0.134

Total cholesterol (mmol/L)

1.278 (1.117–1.461)

0.000

1.722(0.866–3.423)

0.121

Triglycerides (mmol/L)

1.127 (0.879–1.446)

0.346

1.316(0.649–2.671)

0.447

Neutrophils (×10⁹/l)

1.359 (1.127–1.638)

0.001

1.012(0.691–1.481)

0.951

APTT(s)

1.066 (1.019–1.116)

0.006

1.054(0.977–1.137)

0.175

NLR

1.325 (1.109–1.584)

0.002

1.321 (1.104–1.580)

0.002

1.369 (1.141–1.643)

0.001

1.442(1.040–2.000)

0.028