Table 1 Overview of study characteristics
Included studies (First author, year of publication) | Experimental group | Control group | Duration | ||||
|---|---|---|---|---|---|---|---|
Sample size | Mean age (y) | Intervention | Sample size | Mean age (y) | Intervention | ||
Hu et al., 2020 | 678 | 59.4 ± 11.1 | ETV | 216 | 56.1 ± 11.6 | TDF | 5 years |
Byun et al., 2021 | 87 | 56.4 ± 9.4 | TAF | 87 | 53.3 ± 9.5 | TDF | 48 weeks |
Hou et al., 2021 | 227 | 38.00 ± 12.75 | TAF | 107 | 40.00 ± 13.25 | TDF | 144 weeks |
Kim et al., 2020 | 37 | 55.8 ± 7.4 | TDF | 132 | 54.9 ± 7.1 | ETV | 3 years |
Jeong et al., 2021 | 163 | 51.0 ± 12.6 | ETV | 154 | 51.2 ± 10.0 | TDF | 48 weeks |
Jeong et al., 2021(2) | 163 | 51.0 ± 12.6 | ETV | 46 | 51.00 ± 9.26 | TAF | 48 weeks |
Ueno et al., 2019 | 19 | 56.0 ± 10.0 | TDF | 8 | 54.0 ± 10.0 | ETV | 48 weeks |
Lee et al., 2020 | 102 | 54.0 ± 6.4 | TDF | 104 | 54.9 ± 7.8 | ETV | 60 months |
Hagiwara et al., 2019 | 24 | 55.0 ± 12.0 | ETV | 24 | 61.0 ± 13.0 | TAF | 48 weeks |
Hagiwara et al., 2021 | 32 | 54 ± 11 | ETV | 48 | 59.0 ± 12.0 | TAF | 96 weeks |
Inada et al., 2021 | 66 | 68 ± 12 | ETV | 11 | 69.00 ± 7.25 | TAF | 24 weeks |
Inoue et al., 2021 | 12 | 63.0 ± 15.5 | TDF | 7 | 48.0 ± 20.0 | ETV | 24 months |
Itokawa et al., 2021 | 71 | 61.0 ± 12.5 | TAF | 71 | 58.0 ± 11.0 | ETV | 48 weeks |
Kaneko et al., 2019 | 45 | 45.8 ± 14.0 | TDF | 14 | 47.9 ± 10.5 | TAF | 48 weeks |
Uchida et al., 2020 | 92 | 62.0 ± 4.75 | ETV | 127 | 65.0 ± 4.75 | TAF | 48 weeks |
Li et al., 2021 | 75 | 46.5 ± 12.4 | TAF | 75 | 48.7 ± 10.7 | ETV | 24 weeks |
Seto et al., 2018 | 746 | 40.0 ± 11.8 | TAF | 371 | 41.0 ± 12.3 | TDF | 96 weeks |