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Table 1 Comparison of the two groups of the CHB patients in baseline characteristics

From: HBV pregenome RNA as a predictor of spontanous HBeAg seroconversion in HBeAg-positive chronic hepatitis B patients

Characteristics

Group A

(n = 18)

Group B

(n = 36)

t-Test or chi-square

test P values

Univariate logistic regression

P values (OR [95% CI])

Age, years (mean ± SD)

24.06 ± 5.60

25.81 ± 5.50

0.28

0.28 (1.07 [0.95, 1.19])

Gender (M/F)

13/5

26/10

0.62

1.00 (1.00 [0.28, 3.54])

ALT (mean ± SD)

187.53 ± 72.78

158.98 ± 60.64

0.13

0.14 (0.99 [0.99, 1.00])

HBV genotype (No. of genotype B/C)

11/7

20/16

0.46

0.70 (0.80 [0.25, 2.52])

HBsAg, log10 U/ml (mean ± SD)

4.16 ± 0.52

4.29 ± 0.70

0.50

0.49 (1.36 [0.57, 3.26])

HBeAg, log10 PEI-U/ml (mean ± SD)

2.32 ± 0.78

2.60 ± 0.62

0.15

0.15 (1.84 [0.80, 4.24])

HBV DNA, log10 IU/ml (mean ± SD)

7.75 ± 0.68

8.05 ± 0.99

0.24

0.24 (1.47 [0.78, 2.78])

HBV pgRNA, log10 copies/ml (mean ± SD)

7.68 ± 0.84

7.47 ± 0.92

0.42

0.41 (0.76 [0.39, 1.47])

  1. SD Standard deviation, OR Odd ratio, 95% CI 95% confifidence interval