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Table 3 Patient outcomes stratified by histologic subtype and operation

From: Role of colectomy in the management of appendiceal tumors: a retrospective cohort study

Characteristic

Goblet Cell

n (%)

Mucinous

n (%)

Neuroendocrine

n (%)

Non-mucinous

n (%)

Overall

n (%)

Appy

RHC

Appy

RHC

Appy

RHC

Appy

RHC

Appy

RHC

Surgical Margins S1

p = 0.056

p < 0.001

p = 0.015

p < 0.001

p < 0.001

 Negative

127 (91)

197 (97)

170 (90)

303 (98)

2278 (96)

924 (98)

242 (93)

464 (98)

2817 (95)

1888 (98)

 Positive

7 (5)

5 (3)

9 (5)

4 (1)

45 (2)

10 (1)

13 (5)

3 (1)

74 (2)

22 (1)

 Not Evaluable or Unk

6 (4)

2 (1)

10 (5)

1 (< 1)

58 (2)

11 (1)

6 (2)

4 (1)

80 (3)

18 (1)

Surgical Margins S2

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 Negative

321 (85)

831 (97)

504 (80)

1164 (89)

301 (89)

682 (97)

415 (82)

978 (92)

1541 (83)

3655 (93)

 Positive

39 (10)

22 (3)

78 (12)

100 (7)

30 (9)

20 (3)

74 (15)

72 (7)

221 (12)

214 (5)

 Not Evaluable or Unk

16 (4)

8 (1)

51 (8)

49 (4)

8 (2)

3 (< 1)

20 (4)

14 (1)

95 (5)

74 (2)

Surgical Margins S3

0.003

0.090

0.425

0.216

0.008

 Negative

19 (61)

138 (86)

120 (77)

418 (80)

152 (86)

530 (89)

139 (77)

502 (83)

430 (79)

1588 (85)

 Positive

11 (36)

19 (12)

28 (18)

94 (18)

20 (11)

49 (8)

35 (19)

88 (15)

94 (17)

250 (13)

 Not Evaluable or Unk

1 (3)

3 (2)

8 (5)

10 (2)

5 (3)

14 (2)

6 (3)

15 (2)

20 (4)

42 (2)

Surgical Margins S4

0.146

 < 0.001

0.039

0.087

 < 0.001

 Negative

18 (36)

74 (52)

486 (44)

921 (49)

65 (45)

180 (58)

159 (50)

419 (55)

728 (45)

1594 (52)

 Positive

23 (46)

49 (35)

405 (37)

699 (37)

68 (47)

111 (35)

124 (39)

278 (37)

620 (39)

1137 (37)

 Not Evaluable or Unk

9 (18)

19 (13)

205 (19)

251 (13)

12 (8)

22 (7)

37 (12)

60 (8)

263 (16)

352 (11)

Surgical Margins All Stages

 < 0.001

 < 0.001

0.001

 < 0.001

 < 0.001

 Negative

489 (81)

1242 (91)

1351 (63)

2864 (70)

2799 (92)

2317 (91)

1098 (77)

2464 (82)

5737 (80)

8887 (81)

 Positive

80 (13)

95 (7)

520 (24)

898 (22)

163 (5)

191 (7)

249 (18)

442 (15)

1012 (14)

1626 (15)

 Not Evaluable or Unk

32 (5)

32 (2)

275 (13)

311 (8)

83 (3)

50 (2)

76 (5)

95 (3)

466 (6)

488 (4)

30-day Mortality

0.896

0.747

0.049

0.636

0.371

 Alive

494 (99)

1143 (99)

1856 (99)

3579 (99)

2219 (99)

2051 (99)

1189 (98)

2562 (98)

5758 (99)

9335 (98)

 Deceased

4 (1)

10 (1)

28 (1)

50 (1)

19 (1)

31 (1)

29 (2)

56 (2)

80 (1)

147 (2)

 Unknowna

103 (17)

216 (16)

262 (12)

444 (11)

807 (27)

476 (19)

205 (14)

383 (13)

1377 (19)

1519 (14)

90-day Mortality

0.857

0.333

0.004

0.210

0.520

 Alive

485 (99)

1129 (99)

1813 (97)

3508 (97)

2174 (99)

2015 (97)

1150 (95)

2501 (96)

5622 (97)

9153 (97)

 Deceased

7 (1)

15 (1)

64 (3)

106 (3)

33 (1)

57 (3)

62 (5)

110 (4)

166 (3)

288 (3)

 Unknowna

109 (18)

225 (16)

269 (13)

459 (11)

838 (28)

486 (19)

211 (15)

390 (13)

1427 (20)

1560 (14)

Post-Operative Stay

0.891

0.357

 < 0.001

0.994

 < 0.001

 Median (Interquartile Range)

3 (1, 6)

4 (3, 6)

5 (2, 8)

6 (4, 9)

1 (0, 4)

4 (3, 6)

5 (2, 8)

5 (4. 7)

3 (1, 6)

5 (3, 8)

Readmission within 30 Days

0.002

 < 0.001

 < 0.001

0.781

 < 0.001

 No Readmission

554 (92)

1243 (91)

1940 (90)

3679 (90)

2897 (95)

2345 (92)

1289 (91)

2689 (90)

6680 (93)

9956 (91)

 Unplanned Readmission

17 (3)

82 (6)

75 (3)

217 (5)

91 (3)

124 (5)

69 (5)

164 (5)

252 (4)

587 (5)

 Planned Readmission

20 (3)

36 (3)

56 (3)

88 (2)

38 (1)

54 (2)

38 (3)

88 (3)

152 (2)

266 (2)

 Unknown

10 (2)

8 (1)

75 (3)

89 (2)

19 (1)

35 (1)

27 (2)

60 (2)

131 (2)

192 (2)

  1. P-values reflect chi-squared analyses and a two-tailed independent samples t-test assessing for association between outcome and type of operation for each histologic type
  2. Abbreviations: Appy Appendectomy, RHC Right hemicolectomy, S Stage, Unk Unknown
  3. aCases with vital status unknown at 30 days and 90 days (including all cases diagnosed in 2017) were excluded from the analysis