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Table 2 Changes in HCV-related knowledge among clinicians

From: Multi-disciplinary cooperation for the micro-elimination of hepatitis C in China: a hospital-based experience

Questions (Answers)

2021 (158)

2023 (159)

χ2

Number

Rate (%)

Number

Rate (%)

P-value

1. What are the characteristics of hepatitis C? (B and C)

93

58.861

149

93.711

53.289

 A. Most people have obvious symptoms

30

18.987

5

3.145

 

 B. Develops into chronic hepatitis easily

145

91.772

159

100

< 0.001

 C. Develops into liver cirrhosis and cancer

153

96.835

158

99.371

 

 D. Vaccination can prevent hepatitis C infection

43

27.215

10

6.289

 

 E. Unknown

1

0.633

0

0

 

2. What are the transmission routes of hepatitis C? (A, C, and D)

139

87.975

151

94.969

4.975

 A. Blood-borne transmission

153

96.835

159

100

 

 B. Respiratory transmission

5

3.165

1

0.629

0.026

 C. Sexual transmission

150

94.937

153

96.226

 

 D. Maternal-neonatal transmission

153

96.835

159

100

 

 E. Transmission through the digestive tract

10

6.329

1

0.629

 

 F. Unknown

1

0.6333

0

0

 

3. Who are the people at high risk for HCV infection? (A, B, C, D, F, G, and H)

85

53.797

150

94.340

67.927

 A. Those with a history of intravenous drug addiction

153

96.835

159

100

 

 B. Paid blood donors

129

81.646

159

100

< 0.001

 C. Multiple sexual companions

147

93.038

159

100

 

 D. Men who have sex with men

137

86.709

156

98.113

 

 E. Those sharing tableware with patients with hepatitis C

32

20.253

6

3.774

 

 F. Those with exposure of mucous membranes to contaminated blood

153

96.835

159

100

 

 G. Those with tattoos and pierced ears

150

94.937

152

95.597

 

 H. Those with a history of iatrogenic exposure such as surgery and dialysis

152

96.203

157

98.742

 

 J. Unknown

0

0

0

0

 

4. What is the basis of diagnosis for confirmed cases of hepatitis C? (A)

145

91.772

158

99.371

10.84

 A. HCV RNA-positive

145

91.772

158

99.371

 

 B. Anti-HCV-positive

9

5.696

1

0.629

0.001

 C. None of the above

2

1.266

0

0

 

 D. Unknown

2

1.266

0

0

 

5. What period of infection is defined as chronic HCV infection? (B)

133

84.177

153

96.226

13.041

 A. Persistent infection exceeding three months

17

10.759

3

1.887

 

 B. Persistent infection exceeding six months

133

84.177

153

96.226

< 0.001

 C. Persistent infection exceeding 12 months

7

4.430

3

1.887

 

 D. Unknown

1

0.633

0

0

 

6. What are the processes for the management of patients with hepatitis C after the diagnosis? (A, B, and D)

106

67.089

141

88.679

21.471

 A. Reporting of infectious diseases

153

96.835

159

100

 

 B. Clinically diagnosed cases require HCV RNA testing

153

96.835

159

100

< 0.001

 C. Do not intervene unless there is any discomfort

52

32.911

15

9.434

 

 D. Refer cases to the liver clinic for antiviral therapy

133

84.177

159

100

 

 E. Unknown

0

0

0

0

 

7. What is the most effective treatment for hepatitis C? (D)

82

51.899

134

84.277

38.268

 A. Reduce liver enzyme levels

3

1.899

0

0

 

 B. Traditional Chinese treatment

0

0

0

0

< 0.001

 C. Ribavirin and interferon

70

44.304

25

15.723

 

 D. DAAs

82

51.899

134

84.277

 

 E. Unknown

2

1.266

0

0

 

8. Has the country included drugs for HCV treatment in the medical insurance? (A)

146

92.405

159

100

12.551

 A. Yes

146

92.405

159

100

 

 B. No

9

5.696

0

0

< 0.001

 C. Unknown

3

1.899

0

0

 
  1. HCV hepatitis C virus, DAAs direct-acting antiviral agents