Table 2 Clinical characteristics of the patients with moderate-to-severe ulcerative colitis 1 year after diagnosis
Variables, n (%) | Non-SWG group N = 144 | SWG group N = 68 | P-value | ||
|---|---|---|---|---|---|
Age (years), mean (SD) | 40.1 | (16.14) | 38.9 | (14.66) | 0.720 |
≤ 40 | 75 | (52.1) | 38 | (55.9) | 0.605 |
> 40 | 69 | (47.9) | 30 | (44.1) | |
Sex | 0.704 | ||||
Male | 85 | (59.0) | 42 | (61.8) | |
Female | 59 | (41.0) | 26 | (38.2) | |
Disease extent at diagnosis | 0.003 | ||||
Proctitis | 18 | (12.9) | 2 | (3.0) | |
Left-sided colitis | 75 | (53.6) | 27 | (40.9) | |
Extensive colitis | 47 | (33.6) | 37 | (56.1) | |
Disease activity at diagnosisa | 0.168 | ||||
Moderate | 135 | (93.8) | 60 | (88.2) | |
Severe | 9 | (6.3) | 8 | (11.8) | |
Weight loss at diagnosis | 27 | (18.8) | 16 | (23.5) | 0.419 |
Smoking history at diagnosis | 0.276 | ||||
Never | 71 | (50.7) | 36 | (53.7) | |
Past | 60 | (42.9) | 23 | (34.3) | |
Current | 9 | (6.4) | 8 | (11.9) | |
EIMs at diagnosis | 1.000 | ||||
No | 132 | (94.3) | 64 | (95.5) | |
Yes | 8 | (5.7) | 3 | (4.5) | |
Disease activity at 1 yearb | 0.013 | ||||
Remission | 75 | (52.4) | 51 | (75.0) | |
Mild | 50 | (35.0) | 12 | (17.6) | |
Moderate | 16 | (11.2) | 5 | (7.4) | |
Severe | 2 | (1.4) | 0 | (0.0) | |
Number of relapses during the 1 year, mean (SD) | 0.7 | (0.73) | 0.4 | (0.71) | < 0.001 |
Initial systemic steroid use | 68 | (47.2) | 39 | (57.4) | 0.169 |
Exposed medication during the 1 year | |||||
Topical and/or systemic 5-ASA | 144 | (100.0) | 68 | (100.0) | - |
Systemic steroid | 90 | (62.5) | 47 | (69.1) | 0.347 |
Immunomodulators | 46 | (31.9) | 22 | (32.4) | 0.953 |
Biologics | 21 | (14.6) | 5 | (7.4) | 0.134 |