| 1. Men (n = 355) | 2. Pre-menopausal women (n = 417) | 3. Post-menopausal women (n = 108) | P valuea | Post-hocb | ||
---|---|---|---|---|---|---|---|
 |  |  |  |  | 1 vs. 2 | 1 vs. 3 | 2 vs. 3 |
Demographic parameter | Â | Â | Â | Â | Â | Â | Â |
Age (year) | 39 (31, 49) | 33 (28, 38) | 57 (53, 63) | <0.001 | <0.001 | <0.001 | <0.001 |
Body parameters | Â | Â | Â | Â | Â | Â | Â |
BMI (kg/m2) | 29.5 (26.1, 33.1) | 30.1 (27.0, 32.9) | 25.4 (22.95, 28.45) | <0.001 | 1.000 | <0.001 | <0.001 |
WC (cm) | 100.5 (91.4, 112.1) | 98.0 (90.4, 106.5) | 86.7 (80.55, 94.55) | <0.001 | 0.002 | <0.001 | <0.001 |
PBF (%) | 31.5 (27.3, 35.9) | 41.0 (36.9, 44.5) | 37.5 (33.5, 39.8) | <0.001 | <0.001 | <0.001 | <0.001 |
VFA (cm2) | 120.0 (90.4, 161.5) | 160.1 (126.8, 188.7) | 121.0 (100.1, 143.9) | <0.001 | <0.001 | 1.000 | <0.001 |
ASM (kg) | 33.3 (29.8, 37.5) | 25.2 (22.8, 27.7) | 21.2 (19.3, 23.3) | <0.001 | <0.001 | <0.001 | <0.001 |
ASMI (kg/m²) | 8.6 (7.9, 9.3) | 7.3 (6.8, 7.9) | 6.4 (5.9, 6.9) | <0.001 | <0.001 | <0.001 | <0.001 |
FM (kg) | 27.6 (20.7, 35.4) | 31.9 (26.0, 37.9) | 22.9 (19.3, 27.7) | <0.001 | <0.001 | <0.001 | <0.001 |
FFM (kg) | 59.1 (53.2, 66.5) | 45.8 (41.8, 50.2) | 39.5 (36.2, 43.0) | <0.001 | <0.001 | <0.001 | <0.001 |
FFM/FM | 2.18 (1.79, 2.66) | 1.44 (1.25, 1.71) | 1.66 (1.51, 1.99) | <0.001 | <0.001 | <0.001 | 0.004 |
Biochemical parameters | Â | Â | Â | Â | Â | Â | Â |
ALT (U/L) | 36 (22, 61) | 24 (15, 41) | 20 (15, 32) | <0.001 | <0.001 | <0.001 | 0.024 |
AST (U/L) | 23 (18, 35) | 19 (15, 26) | 20 (17, 26) | 0.001 | 0.016 | 0.005 | 0.516 |
AKP (U/L) | 80 (67, 99) | 75 (62, 88) | 86 (76, 101) | <0.001 | <0.001 | 0.101 | <0.001 |
GGT (U/L) | 41 (25, 66) | 26 (17, 42) | 21 (16, 35) | <0.001 | <0.001 | <0.001 | 1.000 |
FBG (mmol/L) | 5.89 (5.52, 7.41) | 5.30 (4.95, 5.85) | 6.68 (5.68, 8.03) | <0.001 | <0.001 | 0.365 | <0.001 |
FINS (µIU/mL) | 10.28 (6.57, 16.69) | 12.18 (7.89, 18.84) | 7.02 (4.59, 10.75) | <0.001 | 0.592 | <0.001 | <0.001 |
HOMA-IR | 2.94 (1.85, 4.65) | 2.95 (1.90, 4.84) | 1.98 (1.34, 3.21) | 0.062 | Â | Â | Â |
TG (mmol/L) | 2.01 (1.30, 2.91) | 1.36 (0.98, 2.00) | 1.54 (1.08, 2.09) | <0.001 | <0.001 | <0.001 | 1.000 |
TC (mmol/L) | 4.99 (4.42, 5.71) | 4.93 (4.43, 5.58) | 5.37 (4.36, 5.90) | 0.236 | Â | Â | Â |
HDL (mmol/L) | 1.23 (1.08, 1.42) | 1.39 (1.22, 1.54) | 1.49 (1.34, 1.74) | <0.001 | <0.001 | <0.001 | <0.001 |
LDL (mmol/L) | 3.10 (2.62, 3.64) | 3.01 (2.54, 3.49) | 3.04 (2.37, 3.66) | 0.172 | Â | Â | Â |
Concomitant diseases | Â | Â | Â | Â | Â | Â | Â |
T2DM | 239 (67.3) | 156 (37.4) | 92 (85.2) | <0.001 | <0.001 | <0.001 | <0.001 |
Dyslipidemia | 180 (50.7) | 115 (27.6) | 36 (33.3) | <0.001 | <0.001 | 0.002 | 0.239 |
Fibroscan | Â | Â | Â | Â | Â | Â | Â |
CAP (dB/m) | 313 (263, 344) | 296 (250, 332) | 267 (231, 306) | <0.001 | 0.003 | <0.001 | <0.001 |
E (kPa) | 6.3 (4.9, 8.1) | 5.3 (4.3, 6.9) | 5.3 (4.2, 6.4) | <0.001 | <0.001 | 0.001 | 0.953 |
Steatosis | Â | Â | Â | <0.001 | <0.001 | <0.001 | <0.001 |
Grade 0 | 99 (27.9) | 147 (35.3) | 55 (50.9) | Â | Â | Â | Â |
Grade 1 | 26 (7.3) | 32 (7.7) | 17 (15.7) | Â | Â | Â | Â |
Grade 2 | 52 (14.7) | 95 (22.8) | 16 (14.8) | Â | Â | Â | Â |
Grade 3 | 178 (50.1) | 143 (34.3) | 20 (18.5) | Â | Â | Â | Â |
Fibrosis | Â | Â | Â | <0.001 | <0.001 | <0.001 | 0.179 |
Stage 0 | 200 (56.34) | 302 (72.4) | 84 (77.8) | Â | Â | Â | Â |
Stage 1 | 43 (12.11) | 40 (9.6) | 9 (8.3) | Â | Â | Â | Â |
Stage 2 | 60 (16.90) | 46 (11.0) | 10 (9.3) | Â | Â | Â | Â |
Stage 3 | 37 (10.42) | 18 (4.3) | 4 (3.7) | Â | Â | Â | Â |
Stage 4 | 15 (4.23) | 11 (2.6) | 1 (0.9) | Â | Â | Â | Â |