Depression symptoms increase the risk for initiation or switching to biologic therapy in pediatric inflammatory bowel disease patients in remission

Table 2 Severity of depression and anxiety symptoms according to disease type

Measure	UC		CD		X²	p-value
Measure	N	%	N	%	X²	p-value
Depression symptoms (PHQ-9)
No symptoms	20	43.5	22	55	2.3	0.50
Mild	15	32.6	13	32.5
Moderate	6	13	2	5
Severe	5	11	3	7.5
Anxiety symptoms (GAD-7)
No symptoms	19	41	20	50	0.87	0.83
Mild	17	37	12	30
Moderate	8	17.4	7	17.5
Severe	2	4.3	1	2.5

Note. X² = chi-squared test of association; UC = Ulcerative colitis; CD Crohn’s Disease

ISSN: 1471-230X