Table 4 Meta-analysis for risk factors of mortality in HBV-ACLF
Risk factors | Combination studies | Heterogeneity of study design | Analysis model | Results of meta-analysis | Begg’s test | Egger’s test | ||
|---|---|---|---|---|---|---|---|---|
P | I2 | OR (95%CI) | P | |||||
INR | 11 |  < 0.001 | 71.5% | Random | 1.923 (1.664, 2.221) |  < 0.001 | 1.000 | 0.628 |
Monocytes | 3 | 0.692 | 0.0% | Fixed | 1.201 (1.113, 1.296) |  < 0.001 | 1.000 | 0.449 |
Cirrhosis | 5 | 0.230 | 27.3% | Fixed | 1.432 (1.210, 1.696) |  < 0.001 | 0.707 | 0.882 |
HE | 11 |  < 0.001 | 79.2% | Random | 2.553 (1.968, 3.312) |  < 0.001 | 1.000 | 0.801 |
HE grade | 3 | 0.177 | 39.1% | Fixed | 2.059 (1.561, 2.717) |  < 0.001 | 1.000 | 0.817 |
SBP | 6 |  < 0.001 | 79.2% | Random | 1.383 (1.080, 1.769) | 0.010 | 1.000 | 0.115 |
Hyponatremia | 2 | 0.814 | 0.0% | Fixed | 1.941 (1.614, 2.334) |  < 0.001 | 1.000 | 0.521 |
HRS | 5 |  < 0.001 | 87.7% | Random | 2.610 (1.669, 4.080) |  < 0.001 | 0.548 | 0.079 |