Acute pancreatitis in intraductal papillary mucinous neoplasm: a single-center retrospective cohort study with systematic review and meta-analysis

Table 4 AP effects on degree of dysplasia and intestinal epithelial subtype in patients with IPMN

Outcomes	IPMN		P-value	Univariate		Multivariate
Outcomes	AP (n = 11)	Non-AP (n = 36)	P-value	OR	95% CI	aOR	95% CI
HGD	4 (36.4)	3 (8.3)	0.042	6.29	1.14–34.57	3.92	0.62–24.85
IC	2 (18.2)	8 (22.2)	1.000	0.78	0.14–4.35	0.69	0.11–4.44
Malignant (HGD + IC)	6 (54.6)	11 (30.6)	0.171	2.73	0.68–10.87	2.00	0.44–9.07
Intestinal epithelial subtype	3 (27.3)	6 (16.7)	0.419	1.88	0.38–9.20	1.92	0.31–11.83

AP: acute pancreatitis; CI: confidence interval; HGD: high grade dysplasia; IC: invasive cancer; IPMN: intraductal papillary mucinous neoplasm; aOR: adjusted odds ratio
Adjusted for smoking and hypertension
Significant values are shown in bold

ISSN: 1471-230X