Table 3 Univariate and Multivariate analysis of factors associated with fistula healing in the training cohort

Sex (female/ male)

1.04

0.25–4.35

0.95

-

-

-

Age (years) (≤ 40/>40)

1.36

0.68–2.70

0.38

-　

-　

-　

BMI(Kg/m²)

  >23.9

-

-

-

-

-

-

  18.5–23.9

1.02

0.53–1.99

0.95

-　

-　

-　

  <18.5

-

-

0.99

-　

-　

-　

Smoking history(no/yes)

1.7

0.88–3.28

0.11

-　

-　

-　

Alcohol intake history(no/yes)

2.53

0.91-7

0.07

4.46

1.16–17.17

0.03

Previous anal surgery(no/yes)

0.66

0.33–1.31

0.23

-

-

-

Classification

  Intersphincteric

-

-

-

-

-

-

  Transsphincteric

0.75

0.34–1.66

0.48

0.76

0.26–2.21

0.62

  Suprasphincteric

0.38

0.13–1.11

0.08

0.17

0.04–0.78

0.02

  Extrasphincteric

0.75

0.04–12.99

0.84

0.45

0-44.35

0.73

Horseshoe fistula (no/yes)

1.14

0.59–2.19

0.69

-

-

-

Recurrent fistula (no/yes)

0.57

0.29–1.15

0.12

-

-

-

CNR (> 63.51/≤63.51)

0.05

0.02–0.12

< 0.01

0.04

0.01–0.1

< 0.01

ADC (10^− 3mm²/s) (> 1.34/≤1.34)

2.86

1.45–5.65

< 0.01

2.78

1.12–6.89

0.03