Efficacy of washed microbiota transplantation for therapeutic targets of refractory functional constipation and the influencing factors: a single-center, retrospective, 24-week follow-up study

Table 1 Baseline definition of each therapeutic target and scoring method

	Scoring method
Target	1	0
Straining^#	Baseline: Straining more than 25% of defecations. Post-WMT: Frequency of straining unchanged or increased compared to baseline	(i) No straining (ii) Straining less than 25% of defecations.
Hard stools^#	Baseline: Lumpy or hard stools more than 25% of defecations. Post-WMT: Frequency of hard stools unchanged or increased compared to baseline	(i) No hard stools (ii) Lumpy or hard stools less than 25% of defecations.
Incomplete evacuation^#	Baseline: Sensation of incomplete evacuation more than 25% of defecations. Post-WMT: Frequency of incomplete evacuation unchanged or increased compared to baseline	(i) No straining (ii) Sensation of incomplete evacuation less than 25% of defecations.
Anorectal obstruction^#	Baseline: Sensation of anorectal obstruction/blockage more than 25% of defecations. Post-WMT: Frequency of anorectal obstruction unchanged or increased compared to baseline	(i) No anorectal obstruction (ii) Sensation of anorectal obstruction/blockage less than 25% of defecations.
Decreased stool frequency^*	Baseline: fewer than three spontaneous complete bowel movements per week. Post-WMT: Frequency of SCBMs/week unchanged or decreased compared to baseline	Three or more spontaneous complete bowel movements per week.

Definition: 1 = With any target at baseline; or frequency unchanged or increased^#/ decreased^* post-WMT compared to baseline. 0 = Without target at baseline; or not matching any criteria compared to baseline
Decreased stool frequency, fewer than three spontaneous complete bowel movements per week; WMT, washed microbiota transplantation

ISSN: 1471-230X