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Table 1 Results of patient demographics

From: Comparison of clinicopathologic characteristics among patients with HBV-positive, HCV-positive and Non-B Non-C hepatocellular carcinoma after hepatectomy: a systematic review and meta-analysis

Variables

No. of studies

No. of patients

RR/MD

95% CIa

Test for overall effect

Heterogeneity

     

P

P

I2 (%)

Age (years)

 NBNC-HCC versus B-HCC

23 [9,10,11, 14, 15, 21,22,23,24,25, 28,29,30, 32, 33, 35,36,37,38,39,40, 43, 46]

7830

10.04

8.55, 11.53

 < 0.00001

 < 0.00001

92

 NBNC-HCC versus C-HCC

21 [9,10,11, 14, 15, 21,22,23,24,25, 28,29,30, 32, 33, 35,36,37, 39, 40, 43]

14,317

0.19

-1.12, 1.50

0.78

 < 0.00001

93

 NBNC-HCC versus BC-HCC

6 [9, 11, 23, 24, 29, 30]

316

6.83

0.18, 13.48

0.04

 < 0.00001

91

Male

 NBNC-HCC versus B-HCC

30 [9,10,11, 13,14,15, 21, 23,24,25,26,27,28,29,30, 32,33,34,35,36,37,38,39,40,41,42,43,44,45,46]

15,160

0.97

0.93, 1.02

0.25

 < 0.00001

69

 NBNC-HCC versus C-HCC

23 [9,10,11, 14, 15, 21, 23,24,25,26,27,28,29,30, 32, 33, 35,36,37, 39, 40, 43, 44]

14,766

1.11

1.06, 1.16

 < 0.00001

0.005

49

 NBNC-HCC versus BC-HCC

7 [9, 11, 23, 24, 27, 29, 30]

520

0.94

0.86, 1.02

0.15

0.87

0

BMI (kg/m2)

 NBNC-HCC versus B-HCC

6 [14, 33, 36, 39, 40, 45]

1183

0.63

0.15, 1.12

0.01

0.04

57

 NBNC-HCC versus C-HCC

5 [14, 33, 36, 39, 40]

2211

0.82

0.04, 1.59

0.05

0.33

12

Diabetes mellitus

 NBNC-HCC versus B-HCC

10 [14, 24, 33, 36, 37, 39, 40, 43,44,45]

1676

2.50

1.87, 3.35

 < 0.00001

0.04

49

 NBNC-HCC versus C-HCC

9 [14, 24, 33, 36, 37, 39, 40, 43, 44]

2791

1.66

1.36, 2.01

 < 0.00001

0.02

57

Child–Pugh grade A

 NBNC-HCC versus B-HCC

19 [11, 13, 15, 22, 24, 26,27,28,29,30, 33, 36,37,38, 40,41,42, 44, 46]

13,282

1.02

0.96, 1.08

0.48

 < 0.00001

94

 NBNC-HCC versus C-HCC

14 [11, 15, 22, 24, 26,27,28,29,30, 33, 36, 37, 40, 44]

12,342

1.04

1.01, 1.06

0.004

0.13

31

 NBNC-HCC versus BC-HCC

5 [11, 24, 27, 29, 30]

436

1.11

1.00, 1.22

0.04

0.67

0

  1. RR Risk Ratio, MD Mean difference, CI Confidence Interval, NBNC-HCC Both HBV and HCV- negative HCC, B-HCC HBV-positive and HCV-negative HCC, C-HCC HBV-negative and HCV-positive HCC, BC-HCC Both HBC and HCV-positive HCC, BMIBody Mass Index
  2. aRR was used to assess dichotomous variables (Male, Diabetes mellitus and Child–Pugh grade A), and MD was used to assess continuous variables (Ages and BMI). The NBNC-HCC group was the reference group
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BMC Gastroenterology

ISSN: 1471-230X

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