Table 3 Univariate analysis of prognostic factors for GC

Age (years) (≥ 65 vs. <65)

1.332

1.013–1.751

0.040*

Sex (male vs. female)

1.063

0.778–1.452

0.703

Tumour Location

< 0.001*

Proximal gastric cancer

1.373

1.026–1.837

0.033*

Distal gastric cancer

1

Total stomach

3.379

1.902–6.004

< 0.001*

Borrmann type (III/IV vs. I/II)

1.340

0.960–1.870

0.080

Lauren type

0.063

Intestinal

1

Diffuse

1.247

0.920–1.691

0.155

Mixed

1.570

1.052–2.344

0.027*

Tumour size (cm) (≥ 5 vs. <5)

1.708

1.273–2.293

< 0.001*

pT stage (T3/4 vs. T1/2)

2.966

1.520–5.788

0.001*

pN stage (N2/3 vs. N0/1)

3.038

2.101–4.392

< 0.001*

pTNM stage (III/IV vs. I/II)

2.299

1.464–3.612

< 0.001*

HER2

1.106

0.704–1.737

0.661

PD-L1

0.991

0.720–1.362

0.953

CLDN18.2 expression

1.366

1.035–1.803

0.028*