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Table 1 Clinical features baseline data

From: Novel nomogram to predict the overall survival of postoperative patients with gastric signet

 

SEER training set

SEER internal validation set

External validation set

P value

Method

n (%)

n (%)

n (%)

Total

3079 (68.1%)

1319 (29.2%)

124 (2.7%)

  

Fustat

 < 0.001

Chisq test

 Death

905 (20%)

442 (9.8%)

66 (1.5%)

  

 Alive

2174 (48.1%)

877 (19.4%)

58 (1.3%)

  

 Futime, median (IQR)

720 (270, 1620)

630 (240, 1560)

1650 (690, 2377.5)

 < 0.001

Kruskal–Wallis

Age

 < 0.001

Chisq test

 ≥ 70

1032 (22.8%)

427 (9.4%)

5 (0.1%)

  

 < 70

2047 (45.3%)

892 (19.7%)

119 (2.6%)

  

Gender

0.010

Chisq test

 Female

1509 (33.4%)

601 (13.3%)

47 (1%)

  

 Male

1570 (34.7%)

718 (15.9%)

77 (1.7%)

  

Primary

 < 0.001

Yates' correction

 Cardia

443 (9.8%)

206 (4.6%)

5 (0.1%)

  

 Fundus of stomach

74 (1.6%)

39 (0.9%)

2 (0%)

  

 Body of stomach

324 (7.2%)

139 (3.1%)

18 (0.4%)

  

 Gastric antrum

865 (19.1%)

361 (8%)

65 (1.4%)

  

 Pylorus

139 (3.1%)

52 (1.1%)

1 (0%)

  

 Lesser curvature of stomach

366 (8.1%)

191 (4.2%)

8 (0.2%)

  

 Greater curvature of stomach

178 (3.9%)

77 (1.7%)

4 (0.1%)

  

 Overlapping lesion of stomach

357 (7.9%)

130 (2.9%)

6 (0.1%)

  

 Stomach-NOS

333 (7.4%)

124 (2.7%)

15 (0.3%)

  

Stage

 < 0.001

Chisq test

 Stage I

874 (19.3%)

333 (7.4%)

30 (0.7%)

  

 Stage II

591 (13.1%)

268 (5.9%)

28 (0.6%)

  

 Stage III

785 (17.4%)

318 (7%)

46 (1%)

  

 Stage IV

829 (18.3%)

400 (8.8%)

20 (0.4%)

  

T

0.019

Chisq test

 T1

572 (12.6%)

208 (4.6%)

17 (0.4%)

  

 T2

1253 (27.7%)

530 (11.7%)

56 (1.2%)

  

 T3

897 (19.8%)

416 (9.2%)

45 (1%)

  

 T4

357 (7.9%)

165 (3.6%)

6 (0.1%)

  

N

0.308

Chisq test

 0

953 (21.1%)

386 (8.5%)

33 (0.7%)

  

 1

1094 (24.2%)

483 (10.7%)

43 (1%)

  

 2

704 (15.6%)

282 (6.2%)

32 (0.7%)

  

 3

328 (7.3%)

168 (3.7%)

16 (0.4%)

  

M

 < 0.001

Chisq test

 M0

2645 (58.5%)

1110 (24.5%)

122 (2.7%)

  

 M1

434 (9.6%)

209 (4.6%)

2 (0%)

  

RNE

0.006

Chisq test

 < 15

1436 (31.8%)

596 (13.2%)

40 (0.9%)

  

 ≥ 15

1643 (36.3%)

723 (16%)

84 (1.9%)

  

LNMR

 < 0.001

Chisq test

 0

1006 (22.2%)

401 (8.9%)

34 (0.8%)

  

 < 30%

683 (15.1%)

310 (6.9%)

45 (1.0%)

  

 ≥ 30% and < 70%

679 (15%)

301 (6.7%)

22 (0.5%)

  

 ≥ 70%

711 (15.7%)

307 (6.8%)

23 (0.5%)

  

Chemotherapy

N/A

N/A

 Chemotherapy

N/A

N/A

74 (59.7%)

  

 No chemotherapy

N/A

N/A

50 (40.3%)

  
  1. Abbreviations: SEER Surveillance, Epidemiology, and End Results, AJCC American Joint Co mmittee on Cancer, RNE Regional nodes examined, LNMR Lymph node metastasis rate
  2. P < 0.05 is considered statistically significant and is represented in bold font