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Table 6 Influencing factors of liver injury in the Omicron BA.5.2 patients

From: Differences in clinical characteristics and liver injury between patients diagnosed with the Omicron subvariant BA.5.2 and the prototype of SARS-CoV-2: a single center retrospective study

   

Univariate analysis

Multivariate analysis

Normal group

Abnormal group

t/χ2

P

Waldχ2

P

N

173

26

    

Male

89 (51.4%)

21 (80.8%)

7.862

0.005

0.000

0.999

Age (years)

51.25 ± 13.54

53.04 ± 13.43

0.627

0.531

  

Vaccination History

171 (98.8%)

26 (100.0%)

0.304

0.589

  

Classification

 Mild

102 (59.0%)

12 (46.2%)

1.515

0.281

  

 Common

71 (41.0%)

14 (53.8%)

    

Comorbidities

43 (24.9%)

6 (23.1%)

0.039

0.844

  

BMI

24.47 ± 3.93

26.70 ± 4.14

2.364

0.020

0.357

0.550

SpO2 (%)

97.44 ± 1.56

97.88 ± 1.21

1.384

0.168

  

T (℃)

37.34 ± 0.95

37.47 ± 1.19

0.613

0.540

  

ALB(g·L-1)

43.83 ± 1.87

43.72 ± 2.73

0.291

0.772

  

WBC(×109 L-1)

1.58 ± 1.50

4.79 ± 1.52

0.657

0.512

  

CRP(mg·L-1)

9.02 ± 11.07

23.01 ± 31.12

4.377

0.000

6.067

0.010

IL-6(pg.mL-1)

10.24 ± 41.36

21.22 ± 40.13

1.047

0.299

  

D-dimer(mg·L-1)

0.34 ± 0.51

0.40 ± 0.35

0.299

0.766

  

PT (second)

10.46 ± 0.78

10.48 ± 1.10

0.074

0.941

  

INR

0.89 ± 0.07

0.90 ± 0.11

0.169

0.866

  

Therapeutic drugs

   Antibiotic

6 (3.5%)

1 (3.8%)

0.009

0.093

  

 Chinese patent medicine

133 (76.9%)

16 (61.5%)

8.827

0.093

  
  1. BMI = Body Mass Index, SpO2 = finger pulse oxygen saturation, T = temperature, ALB = albumin, WBC = white blood cell, IL-6 = Interleukin-6, PT = plasma prothrombin time, INR = International Normalized Ratio