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Table 3 The basic characteristics of patients with hepatocellular carcinoma with central or peripheral invasion

From: Proton beam therapy for hepatocellular carcinoma with bile duct invasion

Basic characteristics

Central (n = 11)

Peripheral (n = 4)

P value

Age (years), median [IQR]

69.0 [63.5, 80.0]

75.5 [70.5, 78.5]

0.69

Sex (Male / Female)

8 (72.7%) / 3 (27.3%)

4 (100.0%) / 0 (0.0%)

0.66

Performance status score (0 / 1–3)

4 (36.4%) / 6 (46.6%)

2 (50.0%) / 2 (50.0%)

0.36

Child (A / B,C)

5 (45.5%) / 6 (54.5%)

3 (75.0%) / 1 (25.0%)

0.56

Etiology (HBV / HCV / NBNC)

2 (18.2%) / 6 (54.5%) / 3 (27.3%)

3 (75.0%) / 1 (25.0%) / 0 (0.0%)

0.55

Tumor characteristics

   

Size, median [IQR], cm

4.0 [3.5, 6.3]

4.4 [3.2, 6.0]

0.94

Number (Solitary / Multiple)

7 (63.6%) / 4 (36.4%)

4 (100.0%) / 0 (0.0%)

0.45

Prior treatment history (No / Yes)

5 (45.5%) / 6 (54.5%)

2 (50.0%) / 2 (50.0%)

0.73

BDTT (No / Yes)

0 (0.0%) / 11 (100.0%)

2 (50.0%) / 2 (50.0%)

0.10

AFP, median [IQR], ng/ml

57.0 [21.6, 315.5]

179.7 [6.3, 3130.7]

1.00

DCP, median [IQR], mAU/ml

48.0 [20.0, 612.0]

27.0 [17.5, 11731.8]

0.84

  1. Abbreviations: HBV, hepatitis B virus; HCV, hepatitis C virus; NBNC, non-HBV/non-HCV; BDI, bile duct invasion; BDTT, bile duct tumor thrombosis; AFP, alpha-fetoprotein; DCP, des-gamma-carboxy prothrombin