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Table 2 Recurrence rate according to the grade of venous invasion

From: Risk stratification for predicting postoperative recurrence of gastric cancer by grade of venous invasion

 

Grade of venous invasion

Total

v0

v1

v2

v3

Total

Recurrence (%)

1/65 (1.5%)

16/54 (29.6%)

10/24 (41.7%)

11/14 (78.6%)

38/157 (24.2%)

 

 RR (95%CI)

Reference

19.3 (3.6–113.3)

27.1 (5.0–162.3)

51.1 (11.1–289.9)

 
 

 *p value

 

< 0.001

< 0.001

< 0.001

 
 

Median DTR (Range)

405

472.5 (42–2111)

351.5 (102–757)

206 (97–771)

369 (42–2111)

Without AC indication

Recurrence (%)

1/59 (1.7%)

2/29 (6.9%)

2/9 (22.2%)

2/5 (40.0%)

7/102 (6.9%)

 

 RR (95%CI)

Reference

4.07 (0.54–30.82)

13.1 (1.8–97.7)

23.6 (3.4–169.1)

 
 

 *p value

 

0.252

0.044

0.014

 
 

Median DTR (Range)

405

354.5 (351–358)

220.5 (182–259)

130.5 (97–164)

259 (97–405)

With AC indication

Recurrence (%)

0/6 (0.0%)

14/25 (56.0%)

8/15 (53.3%)

9/9 (100.0%)

31/55 (56.4%)

 

 RR (95%CI)

Reference

N.C

N.C

N.C

 
 

 *p value

 

0.021

0.046

< 0.001

 
 

Median DTR (Range)

 

644.5 (42–2111)

383 (102–757)

376 (131–771)

394 (42–2111)

  1. *Statistical analysis was performed by Fisher’s exact test. AC adjuvant chemotherapy, RR relative risk, CI confidence interval, DTR days to recurrence, N.C not calculated, v0 no venous invasion, v1 1–3 invasions/slide, v2 4–6 invasions/slide, v3 no less than 7/slide. Filling type of venous invasion in macroscopically identifiable vein with a minor axis of ≥ 1 mm raised the grade of v1 or v2 by 1