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Table 1 Clinicopathologic characteristics of gastric cancer

From: Risk stratification for predicting postoperative recurrence of gastric cancer by grade of venous invasion

Parameters

Total (n = 157)

Recurrence

p value

Yes (n = 38)

No (n = 119)

Age

 Median (range)

72 (42–96)

76 (42–96)

70 (42–92)

0.004

Sex

 Male/Female

111/46

30/8

81/38

0.226

Location

 Upper/Middle/Lower/extending in 2 or 3 regions

32/23/91/11

6/4/23/5

26/19/68/6

0.798

Surgery

 DG/TG/others

104/50/3

24/13/1

80/37/2

0.692

Lymph node dissection

 D1/D1+/D2

13/68/76

3/14/21

10/54/55

0.732

Synchronous multiple GCs

 Yes/No

17/140

4/34

13/106

1.000

Macroscopic type

 0/1/2/3/4/5

78/10/25/17/17/10

3/4/11/7/10/3

75/6/14/10/7/7

< 0.001

Histology

 pap tub1/tub2/muc/por sig nec

41/33/1/82

6/5/1/26

35/28/0/56

0.167

Depth of tumor invasion

 pT1/pT2/pT3/pT4

78/15/42/22

3/3/15/17

75/12/27/5

< 0.001

Cancer stromal volume

 med /int/sci/not described

5/72/38/42

0/18/19/1

5/54/19/41

0.027

Tumor infiltration pattern

 INFa/INFb/INFc/not described

4/70/54/29

1/16/21/0

3/54/33/29

0.220

VI grade

 v0/v1/v2/v3

65/54/24/14

1/16/10/11

64/38/14/3

< 0.001

Lymphatic invasion

 Yes/No

82/75

35/3

47/72

< 0.001

Nodal metastasis

 pN0/pN1/pN2/pN3

91/20/19/27

4/8/9/17

87/12/10/10

< 0.001

Resection margin status

 R0/R1/R2

149/7/1

32/5/1

117/2/0

0.001

pTNM stage

 I/II/III

82/34/41

3/10/25

79/24/16

< 0.001

Neoadjuvant chemotherapy

 Yes/No/unknown

2/140/15

1/35/2

1/105/13

0.444

Adjuvant chemotherapy

 Yes/No/unknown

52/87/18

23/10/5

29/77/13

< 0.001

  1. DG distal gastrectomy, TG total gastrectomy, GC gastric cancer, pap papillary adenocarcinoma, tub1 well-differentiated tubular adenocarcinoma, tub2 moderately differentiated tubular adenocarcinoma, muc mucinous adenocarcinoma, por poorly differentiated adenocarcinoma, either solid or poorly cohesive type, sig signet-ring cell carcinoma, nec neuroendocrine carcinoma, VI venous invasion, pTNM pathological tumor node metastasis, v0 no venous invasion, v1 1–3 invasions/slide, v2 4–6 invasions/slide, v3 no less than 7/slide. Filling type of venous invasion in macroscopically identifiable vein with a minor axis of ≥ 1 mm raised the grade of v1 or v2 by 1