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Table 1 Baseline characteristics of the pathologically-evaluated group and comparison of the pathologically-evaluated normal stomach and others groups

From: Diagnostic performance of the normal range of gastrin calculated using strict criteria based on a combination of serum markers and pathological evaluation for detecting gastritis: a retrospective study

Characteristics

Total (n = 467)

Pathologically-evaluated normal stomach (n = 96)

Others (n = 371)

P-value

Age (years), mean ± SD

49.7 ± 18.4 (16–88)

35.1 ± 15.3

53.4 ± 17.2

< 0.05

Sex (male/female)

268/199

56/40

212/159

0.83

PG I (ng/mL)

43.7 ± 21.5

39.5 ± 12.4

44.8 ± 23.2

< 0.05

PG II (ng/mL)

14.9 ± 8.64

6.67 ± 2.35

17.08 ± 8.37

< 0.05

PG I/II ratio

3.57 ± 1.96

6.13 ± 1.26

2.90 ± 1.50

< 0.05

Gastrin (pg/mL)

159.74 ± 124.41

70.9 ± 27.8

182.5 ± 146.6

< 0.05

Anti-Hp Ab

Positive

327

0

327

< 0.05

Negative

140

96

44

Endoscopic atrophy (negative/positive)

120/347

96/0

24/347

< 0.05

Histologic gastritis (Grade 0/1–3)

Neutrophil activity

105/362

96/0

9/362

< 0.05

 

Inflammation

108/359

96/0

12/359

< 0.05

Atrophy

153/314

96/0

57/314

< 0.05

Intestinal metaplasia

355/112

96/0

259/112

< 0.05

Hp infection

125/342

96/0

29/342

< 0.05

  1. ※Grade 0–4 (0, none; 1, mild; 2, moderate; 3, severe)
  2. anti-Hp Ab anti-Hp antibody, PG Pepsinogen, Hp Helicobacter pylori, SD Standard deviation