Table 3 Metabolites selected by S-plot of the TFK-1 cell line under PF-04691502 treatment

1

Putrescine

0.296

0.958

29

Homocysteine

0.022

0.722

2

Uridine monophosphate

0.095

0.934

30

Ornithine

0.120

0.715

3

Pyruvic acid

0.013

0.933

31

Glucose 6-phosphate

0.047

0.707

4

Taurine

0.261

0.933

32

Asparagine

0.024

0.707

5

Cytosine

0.017

0.918

33

Glucose

0.022

0.705

6

2'-Deoxyuridine

0.006

0.911

34

Niacinamide

-0.049

-0.714

7

4-Aminobutyric acid

0.087

0.908

35

Tryptophan

-0.008

-0.723

8

Guanine

0.008

0.902

36

Methylsuccinic acid

-0.005

-0.729

9

5-Aminovaleric acid

0.056

0.900

37

Galactose

-0.185

-0.730

10

Phosphoenolpyruvic acid

0.029

0.895

38

O-Phospho-Serine

-0.015

-0.763

11

N-Acetylaspartic acid

0.020

0.893

39

3-Hydroxyisovaleric acid

-0.015

-0.770

12

Adenine

0.050

0.882

40

3-Hydroxy-3-methylglutaric acid

-0.009

-0.788

13

Dopamine

0.031

0.874

41

Stearic acid

-0.083

-0.789

14

Cystathionine

0.010

0.861

42

Lyxose

-0.013

-0.821

15

Creatinine

0.050

0.835

43

3-Aminopropanoic acid

-0.120

-0.844

16

2-Phosphoglyceric acid

0.012

0.833

44

Decanoic acid

-0.022

-0.847

17

Malic acid

0.021

0.829

45

Octanoic acid

-0.015

-0.871

18

Glutamine

0.250

0.814

46

Arabinose

-0.014

-0.883

19

Fumaric acid

0.028

0.802

47

Serotonin

-0.014

-0.887

20

Spermidine

0.160

0.798

48

Lauric acid

-0.025

-0.888

21

Histidine

0.180

0.798

49

Nonanoic acid

-0.066

-0.903

22

Citric acid

0.008

0.798

50

Ribulose

-0.023

-0.911

23

Dihydroorotic acid

0.006

0.792

51

Benzoic acid

-0.038

-0.920

24

2-Aminoethanol

0.055

0.790

52

N-Acetyltyrosine

-0.014

-0.929

25

Fructose 1-phosphate

0.113

0.789

53

Glycine

-0.089

-0.944

26

Hydroxylamine

0.178

0.783

54

Dimethylglycine

-0.014

-0.949

27

Spermine

0.019

0.742

55

Nicotinic acid

-0.038

-0.964

28

Saccharopine

0.005

0.735