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Fig. 6 | BMC Gastroenterology

Fig. 6

From: The expression of interleukin-1β in patients with chronic hepatitis B treated with pegylated-interferon-alpha combined with tenofovir disoproxil fumarate and monotherapy

Fig. 6

Anti-HBV activity of IL-1β in hepatoma cells. (a-d) Huh7 cells were transfected with HBV 1.3-mer WT plasmids and cultivated for 24h in the absence (PBS) or presence of IL-1β (100 and 200 ng/ml); (e-h) HepG2.2.15 cells were stimulated with 0 and 200ng/ml IL-1β for 48h; Cells were harvested and subjected to RT-qPCR. The HBsAg and HBeAg in the supernatant were analyzed using ELISA. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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