Albumin infusion may decrease the mortality of hypoalbuminemia patients with severe acute pancreatitis: a retrospective cohort study

Table 3 Univariate and multivariate logistic regression analyses of risk factors for mortality

Variables	Univariate analysis Odds ratio (95%CI)	P	Multivariate analysis Odds ratio (95%CI)	P
Age, years, IQR	1.03(1.02–1.04)	< 0.001	1.02(1.00-1.04)	0.012
Sex (male), n(%)	0.78(0.58–1.04)	0.090
BMI, kg/m², IQR	0.56(0.94–1.02)	0.348
Etiology, n(%)
Biliary	Ref		Ref
Hyperlipidemic	0.66(0.48–0.90)	0.008	1.0(0.52–1.81)	0.919
Alcoholic	1.03(0.57–1.88)	0.926	0.70(0.36–1.35)	0.284
Other	1.14(0.67–1.95)	0.627	1.0(0.42–2.34)	0.991
Hypertension, n(%)	1.33(0.97–1.82)	0.080
Diabetes mellitus, n(%)	1.09(0.73–1.62)	0.672
Laboratory data at admission, IQR
White blood count, × 10⁹/L	1.02(0.99–1.05)	0.090
Hematocrit, %	0.99(0.97-1.00)	0.116
Serum albumin, g/L	0.92(0.89–0.95)	< 0.001	1.03(0.99–1.08)	0.165
Serum urea, mmol/L	1.13(1.11–1.17)	< 0.001	1.08(1.04–1.12)	< 0.001
Serum creatinine, µmol/L	1.01(1.00-1.01)	< 0.001	1.00(0.99-1.00)	0.331
Serum calcium, mmol/L	0.19(0.12–0.31)	< 0.001	0.27(0.14–0.50)	< 0.001
Serum albumin _min, g/L	0.90(0.87–0.93)	< 0.001	0.93(0.89–0.97)	0.002
SIRS score ≥ 2, n(%)	1.47(1.01–2.14)	0.045	1.16(0.75–1.80)	0.506
APACHE≥score ≥ 15, n(%)	3.12(2.26–4.3)	< 0.001	1.73(1.19–2.51)	0.004

IQR, Inter Quartile Range; BMI, Body Mass Index; Serum albumin _min, the lowest albumin level within 1 week after admission; SIRS, Systemic Inflammatory Response Syndrome; APACHE, Acute Physiology and Chronic Health Evaluation

ISSN: 1471-230X