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Table 2 Risk factor determination by univariate analysis for DFS or OS

From: Postoperative serum interleukin-6 levels correlate with survival in stage I-III colorectal cancer

 

DFS

OS

 

P

HR

95%CI

P

HR

95%CI

Age (y)

      

< 60

1

  

1

  

≥ 60

0.60

1.16

0.66–2.05

0.34

1.38

0.71–2.69

Gender

      

Male

1

  

1

  

Female

0.01*

0.39

0.20–0.76

0.08

0.52

0.25–1.07

Type of operation

      

Laparotomy

1

  

1

  

Laparoscopy

0.02*

0.51

0.28–0.90

0.02*

0.46

0.23–0.89

Tumor location

      

Right

1

  

1

  

Left

0.97

0.99

0.53–1.82

0.59

0.81

0.39–1.71

History of smoking

      

Current + past

1

  

1

  

Never

0.86

0.96

0.54–1.71

0.58

0.83

0.43–1.60

History of drinking

      

Current + past

1

  

1

  

Never

0.02*

0.51

0.30–0.88

0.15

0.63

0.34–1.19

Histological grade

      

Well + moderate

1

  

1

  

Poor

0.44

1.35

0.63–2.86

0.56

1.30

0.54–3.10

Mucinous elements

      

Without

1

  

1

  

With

0.85

1.07

0.52–2.20

0.81

1.11

0.49–2.50

T stages

      

T1 + T2

1

  

1

  

T3 + T4

0.07

2.56

0.92–7.09

0.07

3.79

0.91–15.75

 N stages

      

N0

1

  

1

  

N1+N2

< 0.01*

2.55

1.45–4.50

< 0.01*

2.87

1.47–5.60

TNM stages

      

I + II

1

  

1

  

III

< 0.01*

2.55

1.45–4.50

< 0.01*

2.87

1.47–5.60

BMI (kg/m 2 )

0.44

0.97

0.89–1.05

0.15

0.93

0.84–1.03

IL-6 level

      

Low

1

  

1

  

High

0.02*

1.96

1.13–3.38

0.14

1.62

0.86–3.05

  1. *with significant difference DFS: disease free survival; OS: overall survival; BMI: body mass index
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BMC Gastroenterology

ISSN: 1471-230X

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