Fig. 2

CD4⁺CD25^hiCD127^low Tregs were up-regulated in patients with gastrointestinal cancer. A Percentage of CD4⁺ cells amongst patients and healthy controls. B Percentage of CD4⁺CD25hi cells amongst patients and healthy controls. C Percentage of CD4⁺CD25^hiCD127^low cells amongst patients and healthy controls. D Percentage of CD4⁺CD25^hi cells amongst CD4⁺ cells. E Percentage of CD4⁺CD25^hiCD127^low cells amongst CD4⁺ cells. HC, healthy control (N = 50); GC, gastric cancer (N = 45); CRC, colorectal cancer (N = 50). N, number of patients or healthy controls. Data were presented as means ± SEM and analyzed by Student’s t test. *, P < 0.05; **, P < 0.01; ***, P < 0.001