Table 3 Details of the genetic variants with potential pleiotropy among instrumental variables used for gut microbiota
Gut microbiota | SNP | Pleiotropic Trait | p-value | PMID |
|---|---|---|---|---|
Phylum Actinobacteria | rs7570971 | Low density lipoprotein cholesterol measurement, alcohol drinking | 1.00E-13 | 30698716 |
| Â | Â | Total cholesterol measurement | 1.00E-13 | 24097068 |
| Â | Â | Blood metabolite measurement | 8.00E-45 | 24816252 |
| Â | Â | Body mass index | 5.00E-09 | 26426971 |
Genus Eubacterium hallii group | rs281379 | Pubertal anthropometrics | 5.00E-08 | 23449627 |
| Â | Â | Crohn's disease | 7.00E-12 | 21102463 |
| Â | Â | Childhood asthma with severe exacerbations | 3.00E-09 | 33328473 |
| Â | Â | Alcohol consumption (drinks per week) (MTAG) | 4.00E-21 | 30643251 |
| Â | Â | Serum levels of protein FUT3 | 3.00E-16 | 35078996 |
Genus Flavonifractor | rs6761463 | Adult body size | 1.00E-11 | 32376654 |
Genus Ruminiclostridium6 | rs11992182 | lymphocyte count | 2.00E-12 | 32888494 |