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Table 4 Changes in quality of life as evaluated by the SF-36 questionnaire from baseline to week 16 within each group

From: Branched-chain amino acids supplementation improves liver frailty index in frail compensated cirrhotic patients: a randomized controlled trial

SF-36 questionnaire (mean ± SD)

BCAA group

Control group

Baseline

At 16 weeks

P-value

Baseline

At 16 weeks

P-value

Physical function

61.0 ± 25.3

73.8 ± 21.4

< 0.001

65.0 ± 23.8

65.2 ± 21.9

0.9

Role physical

73.0 ± 27.9

88.0 ± 17.9

0.006

66.0 ± 26.9

61.0 ± 30.7

0.096

Bodily pain

73.9 ± 20.2

82.6 ± 14.1

0.02

74.4 ± 16.9

75.1 ± 15.8

0.66

General health

55.8 ± 19.6

65.0 ± 16.9

0.02

52.4 ± 17.4

54.0 ± 18.3

0.43

Physical component score

44.1 ± 8.0

49.1 ± 6.9

< 0.001

44 ± 8

43.1 ± 8.2

0.08

Role emotion

81.3 ± 23.7

90.7 ± 15.3

0.09

74.7 ± 24.1

78.7 ± 23.3

0.33

Vitality

68.0 ± 17.7

74.6 ± 13.1

0.03

68.0 ± 16.4

69.8 ± 14.5

0.29

Mental health

82.1 ± 13.6

85.3 ± 10.3

0.18

81.9 ± 11.4

83.8 ± 9.8

0.13

Social functioning

75.0 ± 19.4

80.0 ± 17.7

0.08

77.0 ± 15.6

80.5 ± 14.9

0.07

Mental component score

55.2 ± 6.2

56.7 ± 4.5

0.2

53.7 ± 5.6

54.9 ± 5.6

0.07