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Table 3 Comparison of changes in parameters from baseline to week 16 between 2 groups

From: Branched-chain amino acids supplementation improves liver frailty index in frail compensated cirrhotic patients: a randomized controlled trial

Delta (baseline and week 16)

BCAA group

Control group

P-value*

∆ BMI (kg/M2)

0.51 ± 1.19

-0.49 ± 1.89

0.05

∆ Albumin (g/dL)

0.26 ± 0.27

0.06 ± 0.3

0.02

∆ Child-Pugh score

-0.36 ± 0.9

0.08 ± 1.08

0.46

∆ MELD score

-0.4 ± 2.02

-0.04 ± 2.46

0.67

∆ MELD-Na score

-0.64 ± 1.73

-0.68 ± 3.1

0.61

∆ LFI

- ∆ HGS (kg)

- ∆ CST (sec)

- ∆ Balancing test (sec)

-0.36 ± 0.3

6.63 ± 3.77

-9.28 ± 11.05

3.52 ± 3.18

-0.15 ± 0.28

5.69 ± 3.13

-2 ± 4.04

1.32 ± 3.49

0.01

0.52

< 0.01

0.02

Body composition

   

- ∆ Muscle mass (kg)

- ∆ SMI (kg/m2)

- ∆ Fat free mass (kg)

0.52 ± 1.31

0.21 ± 0.52

-0.15 ± 2.36

-0.03 ± 2.56

-0.01 ± 1.04

0.40 ± 4.06

0.08

0.07

0.85

  1. *By non-parametric Mann–Whitney U test
  2. BMI, body mass index; MELD, model for end-stage liver disease; LFI, liver frailty index; HGS, hand grip strength; CST, chair stands test; SKI, skeletal muscle index