Peripheral blood T-lymphocyte subsets are potential biomarkers of disease severity and clinical outcomes in patients with ulcerative colitis: a retrospective study

Table 3 Area under ROC curves, cut-off value, sensitivity and specificity of T-lymphocyte subsets in assessing the disease severity of UC patients

Variables	AUC	95%CI	P value	Cut-off value	Sensitivity (%)	Specificity (%)
CD8⁺T cells	0.677	0.575-0.779	0.002	27.03%	71.05	65.38
CD4⁺/CD8⁺ ratio	0.669	0.568-0.771	0.003	1.73	53.85	78.95
CD4⁺CD25⁺T cells	0.631	0.523-0.740	0.022	3.05%	61.54	63.16
CD3⁺HLA-DR⁺T cells	0.885	0.822-0.948	<0.001	5.33%	76.32	89.74
ESR	0.797	0.716-0.878	<0.001	16.50 mm/h	76.32	74.36
CRP	0.878	0.815-0.941	<0.001	9.30 mg/L	76.32	87.18
CD3⁺HLA-DR⁺T cells and CRP	0.929	0.882-0.976	<0.001	0.24	89.47	85.90

UC ulcerative colitis, ESR erythrocyte sedimentation rate, CRP C-reactive protein, ROC receiver operating characteristic, AUC area under the curve, CI confidence interval.

ISSN: 1471-230X