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Table 2 Distribution of T-lymphocyte subsets in ulcerative colitis (UC) patients and healthy controls (HC)

From: Peripheral blood T-lymphocyte subsets are potential biomarkers of disease severity and clinical outcomes in patients with ulcerative colitis: a retrospective study

Variables

UC (n=116)

Mild activity(n=37)

Moderate activity

(n=41)

Severe activity (n=38)

HC (n=90)

P value a

P value b

P value c

P value d

CD3+T cells (%)

74.75±8.21

73.96±9.23

74.22±7.22

76.10±8.22

74.76±6.90

0.998

0.890

0.264

0.314

CD4+T cells (%)

42.85±9.77

43.27±9.18

44.73±10.39

40.40±9.36

45.71±7.94

0.021*

0.508

0.059

0.049*

CD8+T cells (%)

27.88±8.86

26.98±7.98

25.46±9.15

31.35±8.49

25.00±6.47

0.008*

0.436

0.029*

0.003*

CD4+/CD8+ ratio

1.75±0.81

1.78±0.77

2.02±0.91

1.43±0.61

2.00±0.77

0.025*

0.176

0.050

0.001*

CD4+CD25+T cells (%)

3.14±1.24

3.46±1.07

3.11±1.23

2.86±1.35

3.12±1.74

0.927

0.211

0.034*

0.355

CD3+HLADR+T cells (%)

5.22±5.47

2.80±1.55

4.06±5.01

8.83±6.55

4.60±2.56

0.278

0.256

<0.001*

<0.001*

  1. UC ulcerative colitis, HC healthy controls.
  2. *P<0.05 was considered statistically significant.
  3. P value a, comparing UC and HC
  4. P value b, comparing mildly active subgroup and moderately active subgroup
  5. P value c, comparing mildly active subgroup and severely active subgroup
  6. P value d, comparing moderately active subgroup and severely active subgroup
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BMC Gastroenterology

ISSN: 1471-230X

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