Fig. 2

Mutational landscape and genomic pattern of patients with high or low TFB in the MSS and non-EBV (+) cohort. (A) The mutation spectrum of high/low TFB groups; (B-E) Comparisons of copy number score (B), LOH fraction (C), tumor neoantigen burden (D), and tumor mutation burden (E) between TFB-high and TFB-low groups. Data were analyzed by Wilcox test. Significant differences: *p < 0.05, **p < 0.01, ***p < 0.001. No significant difference is indicated as ns