Table 4 Cox regression hazard ratio in the univariate and multivariate analyses for surgery in patients with Crohn’s disease
From: The effect of biological agent on body composition in patients with Crohn’s disease
Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Myopenia | 2.759 (0.812–9.375) | 0.104 | 0.739 (0.185–2.948) | 0.668 |
Male sex | 8.859 (1.182–66.4) | 0.034 | 17.217 (1.542–192.250) | 0.021 |
Age | 0.975 (0.927–1.026) | 0.329 | ||
BMI | 0.997 (0.884–1.124) | 0.961 | ||
Age at diagnosis (years) | ||||
A2 (18–40) | Ref | |||
A3 (> 40) | 0.963 (0.321–2.893) | 0.946 | ||
Location | ||||
L1(Ileum) | Ref | Ref | ||
L2(Colon) | 0.697 (0.233–2.087) | 0.519 | 1.279 (0.390–4.194) | 0.684 |
L3(Ileocolon) | 0.338 (0.117–0.979) | 0.046 | 0.464 (0.144–1.494) | 0.198 |
L4(Upper GI) | 0.947 (0.698–1.286) | 0.729 | ||
Behavior | ||||
B1(Inflammatory) | Ref | Ref | ||
B2(Stricturing) | 2.056 (0.797–7.878) | 0.116 | 1.709 (0.483–6.051) | 0.406 |
B3(Penetrating) | 3.395 (0.956–12.056) | 0.059 | 5.399 (1.311–22.241) | 0.020 |
P(Perianal disease) | 0.482 (0.205–1.136) | 0.095 | 0.396 (0.150–1.047) | 0.062 |
Disease duration | 1.039 (0.960–1.125) | 0.344 | ||
Biologics | ||||
Biologics one | Ref | |||
Biologics 2 or more | 1.157 (0.337–3.974) | 0.817 | ||
Biologics duration | 1.003 (0.993–1.014) | 0.554 | ||
Laboratory parameters | ||||
Hemoglobin | 0.950 (0.770–1.173) | 0.636 | ||
Albumin | 0.736 (0.355–1.527) | 0.411 | ||
CRP | 0.940 (0.838–1.054) | 0.288 | ||
CT parameter value | ||||
SMA | 1.005 (0.992–1.017) | 0.466 | ||
PMA | 1.027 (0.972–1.085) | 0.342 | ||
SFA | 0.991 (0.981–1.001) | 0.075 | 0.963 (0.777–1.193) | 0.731 |
VFA | 0.985 (0.966–1.003) | 0.103 | 0.934 (0.754–1.155) | 0.527 |
TFA | 0.994 (0.987–1.000) | 0.053 | 1.044 (0.844–1.292) | 0.693 |
IMFA | 0.973 (0.935–1.012) | 0.166 | 0.952 (0.767–1.182) | 0.656 |