Fig. 4
From: APC mutation correlated with poor response of immunotherapy in colon cancer
The association between APC mutation and TMB, immune checkpoint molecules expression, mean CpG methylation and tumor purity. (A) APC mutation was associated with a lower TMB. (B-D) APC mutation was correlated with lower expression of PDCD1 (PD-1), CD274 (PD-L1) and PDCD1LG2 (PD-L2). (E) APC status was not associated with CpG methylation level. (F) APC mutation was associated with higher tumor purity