Table 1 Sources of information/ electronic databases and search strategies medline

#1 (Inflammatory Bowel Diseases [MESH] OR Inflammatory Bowel Disease [TIAB] OR Bowel Diseases Inflammatory [TIAB] OR Crohn Disease [MESH] OR Crohn Disease [TIAB] OR Crohn's Disease [TIAB] OR Ulcerative Colitis [TIAB] OR Idiopathic Proctocolitis [TIAB] OR Proctocolitis [TIAB])

#2 (Sulfhydryl Compounds [MESH] OR Compounds Sulfhydryl [TIAB] OR Sulfhydryl Compound [TIAB] OR Thiol [TIAB] OR Thiol* [TIAB])

#1 AND #2

PMC

#1 (Inflammatory Bowel Diseases [MESH] OR Inflammatory Bowel Disease [Title] OR Crohn Disease [MESH] OR Crohn Disease [Title] OR Crohn's Disease [Title] OR Ulcerative Colitis [Title] OR Proctocolitis [Title])

#2 (Sulfhydryl Compounds [MESH] OR Sulfhydryl Compound [Title] OR Thiol [Title] )

#1 AND #2

BVS

#1 (mh: "Doenças Inflamatórias Intestinais" OR mh: "Inflammatory Bowel Diseases" OR tw: "Doenças Inflamatórias Intestinais" OR tw: "Inflammatory Bowel Diseases" OR tw: "Doenças Inflamatórias do Intestino" OR mh: "Doença de Crohn" OR tw: "Doença de Crohn" OR mh: "Crohn Disease" OR tw: "Crohn Disease" OR mh: "Colitis, Ulcerative" OR tw: "Colitis Ulcerative" OR mh: "Colite Ulcerativa" OR tw: "Colite Ulcerativa")

#2 (mh: "Compostos de Sulfidrila" OR tw: "Compostos de Sulfidrila" OR mh: "Sulfhydryl Compounds" OR tw: "Sulfhydryl Compounds" OR tw:"Thiol")

#1 AND #2

LILACS

#1 (mh: "Doenças Inflamatórias Intestinais" OR mh: "Inflammatory Bowel Diseases" OR tw: "Doenças Inflamatórias Intestinais" OR tw: "Inflammatory Bowel Diseases" OR tw: "Doenças Inflamatórias do Intestino" OR mh: "Doença de Crohn" OR tw: "Doença de Crohn" OR mh: "Crohn Disease" OR tw: "Crohn Disease" OR mh: "Colitis, Ulcerative" OR tw: "Colitis Ulcerative" OR mh: "Colite Ulcerativa" OR tw: "Colite Ulcerativa")

#2 (mh: "Compostos de Sulfidrila" OR tw: "Compostos de Sulfidrila" OR mh: "Sulfhydryl Compounds" OR tw: "Sulfhydryl Compounds" OR tw:"Thiol")

#1 AND #2

SCOPUS

#1 TITLE-ABS-KEY ( "inflammatory bowel diseases" OR "inflammatory bowel disease" OR "bowel diseases inflammatory" OR "crohn disease" OR "crohn's disease" OR "ulcerative colitis" OR "idiopathic proctocolitis" OR "proctocolitis" )

#2 TITLE-ABS-KEY ( "Sulfhydryl Compounds" OR "Compounds Sulfhydryl" OR "Sulfhydryl Compound" OR thiol* )

#1 AND #2

WOS

#1 ALL= ("inflammatory bowel diseases" OR "inflammatory bowel disease" OR "bowel diseases inflammatory" OR "crohn disease" OR "crohn's disease" OR "ulcerative colitis" OR "idiopathic proctocolitis" OR "proctocolitis")

#2 ALL= ("Sulfhydryl Compounds" OR "Compounds Sulfhydryl" OR "Sulfhydryl Compound" OR thiol*)

#1 AND #2

EMBASE

#1 'inflammatory bowel diseases'/exp OR 'inflammatory bowel diseases' OR 'crohn disease'/exp OR 'crohn disease' OR 'ulcerative colitis'/exp OR 'ulcerative colitis' OR 'idiopathic proctocolitis' OR 'proctocolitis'/exp OR 'proctocolitis'

#2 'inflammatory bowel diseases'/exp OR 'inflammatory bowel diseases' OR 'crohn disease'/exp OR 'crohn disease' OR 'ulcerative colitis'/exp OR 'ulcerative colitis' OR 'idiopathic proctocolitis' OR 'proctocolitis'/exp OR 'proctocolitis'

#1 AND #2

CINAHL

#1 (Inflammatory Bowel Diseases [MESH] OR Inflammatory Bowel Disease [TIAB] OR Bowel Diseases Inflammatory [TIAB] OR Crohn Disease [MESH] OR Crohn Disease [TIAB] OR Crohn's Disease [TIAB] OR Ulcerative Colitis [TIAB] OR Idiopathic Proctocolitis [TIAB] OR Proctocolitis [TIAB])

#2 (Sulfhydryl Compounds [MESH] OR Compounds Sulfhydryl [TIAB] OR Sulfhydryl Compound [TIAB] OR Thiol [TIAB] OR Thiol* [TIAB])

#1 AND #2

COCHRANE

#1 MeSH descriptor: [Inflammatory Bowel Diseases] explode all trees

#2 Inflammatory Bowel Disease OR Bowel Diseases Inflammatory

#3

#1 OR #2

#4 MeSH descriptor: [Crohn Disease] explode all trees

#5 Crohn Disease OR Crohn's Disease OR Ulcerative Colitis OR Idiopathic Proctocolitis OR Proctocolitis

#6

#4 OR #5

#7

#3 OR #6

#8 MeSH descriptor: [Sulfhydryl Compounds] explode all trees

#9 Compounds Sulfhydryl OR Sulfhydryl Compound OR Thiol*

#10

#8 OR #9

#11

#7 AND #10

OVID

(Inflammatory Bowel Diseases and Sulfhydryl Compounds).af.

CTGOV

Inflammatory Bowel Disease OR Bowel Diseases Inflammatory OR Crohn Disease OR Crohn's Disease OR Ulcerative Colitis OR Idiopathic Proctocolitis OR Proctocolitis Compounds | Sulfhydryl OR Sulfhydryl Compound OR Thiol*

WHO

Inflammatory Bowel Disease OR Bowel Diseases Inflammatory OR Crohn Disease OR Crohn's Disease OR Ulcerative Colitis OR Idiopathic Proctocolitis OR Proctocolitis Compounds | Sulfhydryl OR Sulfhydryl Compound OR Thiol*

OPENGREY

#1 ("inflammatory bowel diseases" OR "inflammatory bowel disease" OR "bowel diseases inflammatory" OR "crohn disease" OR "crohn's disease" OR "ulcerative colitis" OR "idiopathic proctocolitis" OR "proctocolitis")

BDTD

(Inflammatory Bowel Diseases and Sulfhydryl Compounds)

ICTRP

(Inflammatory Bowel Diseases and Sulfhydryl Compounds)

CAPES

("inflammatory bowel diseases" OR "inflammatory bowel disease" OR "bowel diseases inflammatory" OR "crohn disease" OR "crohn's disease" OR "ulcerative colitis" OR "idiopathic proctocolitis" OR "proctocolitis") AND ("Sulfhydryl Compounds" OR "Compounds Sulfhydryl" OR "Sulfhydryl Compound" OR thiol*)