Table 2 Univariate and multivariate analyses for OS in EGC patients with neoadjuvant chemotherapy

Age

 ≤ 60

Reference

Reference

 > 60

1.033

0.826–1.291

0.778

1.210

0.959–1.528

0.109

Year of diagnosis

 2006–2011

Reference

Reference

 2012–2017

0.900

0.717–1.130

0.363

0.871

0.687–1.103

0.250

Sex

 Male

Reference

Reference

 Female

0.930

0.690–1.252

0.631

0.922

0.676–1.256

0.605

Race

 White

Reference

Reference

 Black

0.775

0.461–1.305

0.338

0.635

0.369–1.091

0.100

 Others

0.848

0.578–1.244

0.400

0.827

0.555–1.232

0.351

Grade

 Well/moderately differentiated

Reference

Reference

 Poorly differentiated/undifferentiated

1.416

1.094–1.831

0.008

1.298

0.986–1.709

0.063

 Others

1.102

0.634–1.914

0.731

1.145

0.652–2.012

0.637

Histology

 Adenocarcinomas

Reference

Reference

 Others

1.270

0.972–1.659

0.080

1.107

0.831–1.473

0.487

Marital status

 Married

Reference

Reference

 Others

1.100

0.864–1.401

0.439

1.266

0.983–1.630

0.068

T-category

 T1

Reference

Reference

 T2

1.659

1.079–2.550

0.021

1.484

0.946–2.328

0.086

 T3

2.674

1.713–4.173

 < 0.001

2.019

1.255–3.246

0.004

 T4

2.292

1.299–4.043

0.004

1.815

0.993–3.317

0.053

N-category

 N0

Reference

Reference

 N1

1.705

1.262–2.305

0.001

1.488

1.080–2.049

0.015

 N2

2.649

1.828–3.838

 < 0.001

2.377

1.593–3.547

 < 0.001

 N3

4.133

2.565–6.660

 < 0.001

4.306

2.562–7.237

 < 0.001

No. of LN examination

 1–9

Reference

Reference

 10–19

1.248

0.891–1.747

0.198

0.933

0.655–1.329

0.701

 > 19

0.864

0.616–1.212

0.397

0.593

0.412–0.854

0.005