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Table 2 Demographics and clinical characteristics of CLD patients awaiting liver transplant scored as A, B, or C using the Child-Turcotte-Pugh scoring system (CTP-A, CTP-B, or CTP-C)

From: Potential utility of a multi-component coagulation factor panel to calculate MELD scores and assess the risk of portal vein thrombosis in chronic liver disease

 

CTP-A (n = 12)

CTP-B (n = 28)

CTP-C* (n = 3)

p value

Age

59.5 (56.5–61.5)

59 (52–65)

55 (41–69)

0.9678

Sex [n (%)]

 Male

11 (92)

18 (64)

3 (100)

 

 Female

1 (8)

10 (36)

0 (0)

 

Race (n)

 White

11

27

3

 

 Black

0

1

0

 

 Other

1

0

0

 

Etiology (n)

 ASH

7

10

2

 

 NASH

7

16

1

 

 HCV

6

2

1

 

 Mixed liver disease

8

3

1

 

 Portal vein thrombosis

1

2

1

 

MELD-Na score

10 (9–12)

15 (11–17)

19 (16–20)

0.0022

Serum sodium

139 (138–140)

137 (135–138)

138 (134–139)

0.0281

Serum creatinine

0.79 (0.73–1.26)

0.91 (0.71–1.23)

1.02 (0.79–1.12)

0.9540

Total bilirubin

1.1 (0.7–1.4)

1.9 (1.3–2.7)

5.2 (2.4–6.9)

0.0009

PT/INR

1.2 (1.1–1.3)

1.4 (1.2–1.5)

1.6 (1.5–1.7)

0.0019

Serum albumin

3.8 (3.7–3.9)

3.4 (3.2–3.7)

2.5 (2.5–3.2)

0.0019

FV (%)

79 (66–100)

65 (45–81)

40 (39–44)

0.0175

FVIII (%)

259 (215–278)

253 (193–312)

233 (227–291)

0.6888

PC (%)

66 (48–84)

53 (35–63)

22 (21–41)

0.0346

PS (%)

59 (47–76)

59 (50–67)

66 (61–69)

0.5805

D-Di (ng/m)

0.85 (0.54–1.36)

2.94 (1.52–6.56)

3.50 (2.20–9.61)

0.0345

sP selectin (pg/m)

43 (39–47)

57 (41–67)

49 (39–71)

0.0973

asTF (ng/m)

1.011 (0.445–2.503)

0.456 (0.333–0.986)

0.133, 0.254**

0.1725

Novel CLD score

11.2 (9.4–12.8)

14.8 (12.5–18.3)

21.8 (21.3–22.5)

0.0032

  1. Presented as median with interquartile range. *median, min, and max reported due to low n. **only 2 CTP-C patients had detectable levels of asTF, both values given. p values were assessed via one-way ANOVA to determine if the variance across the groups was significant