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Table 1 Clinical characteristics of the study population

From: Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study

 

CD (n = 610)

UC/IC (n = 468)

Controls (n = 365)

p-value

Gender [n (%)]

    

  Male

271 (44.4%)

232 (49.6)

130 (35.6)

0.001

  Female

339 (55.6%)

236 (50.4)

235 (64.4)

 

Age [y]

48.5, 15.5

50, 14

36, 9

0.0001

  (Mean, SD, range)

18–87

19–85

18–75

 

BMI [kg/m2]

23.6, 3.6

24.5, 3.7

21.3, 3.1

0.224

  (Mean, SD, range)

18–30

18–31.5

18–25

 

Age at diagnosis [y]

31, 14

34, 14

 

0.0001

  (Mean, SD, range)

1–75

8–78

  

Disease duration [y]

18, 11

16, 10

 

0.0034

  (Mean, SD, range)

0–53

0–52

  

CDAI

20, 41

   

  (Median, IQR, range)

0–230

   

MTWAI

 

1, 3

  

  (Median, IQR, range)

 

0–17

  

Smoking status at diagnosis [n (%)]

    

  Non-smoker

350 (57.7)

371 (75.7)

 

0.001

  Smoker

235 (38.7)

93 (19)

  

  Unknown

22 (3.6)

26 (5.3)

  

Current smoking status [n (%)]

    

  Non-smoker

453 (74.6)

319 (85.5)

 

0.001

  Smoker

151 (24.9)

66 (13.5)

  

  Unknown

3 (0.5)

5 (1)

  

Therapy history (ever treated with) [n (%)]

    

  5-ASA

369 (60.8)

471 (96.0)

 

0.001

  Steroids

528 (87)

398 (81)

 

0.009

  Immunomodulators

492 (81.1)

300 (61.2)

 

0.001

  Anti-TNF

384 (63.3)

169 (34.5)

 

0.001

EIM [n (%)]

    

  Any

380 (62.6)

219 (44.7)

 

0.001

  Arthritis

330 (54.4)

173 (35.3)

 

0.001

  Uveitis/Iritis

79 (13)

30 (6.1)

 

0.001

  Pyoderma gangraenosum

8 (1.3)

9 (1.8)

 

0.489

  Erythema nodosum

62 (10.2)

15 (3.1)

 

0.001

  Aphtous/Oral ulcers

93 (15.3)

25 (5.1)

 

0.001

  Ankylosing spondylitis

38 (6.3)

16 (3.3)

 

0.023

  PSC

8 (1.3)

15 (3.1)

 

0.045

Complications [n (%)]

    

  Perianal fistula

164 (27)

–

  

  Other fistula

111 (18.3)

   

  Abscess

137 (22.6)

   

  Stenosis

264 (43.5)

   

Surgery history [n (%)]

    

  Any

313 (51.6)

53 (10.8)

 

0.001

  Intestinal surgery

258 (42.5)

46 (9.4)

 

0.001

  Fistulas or abscess surgery

147 (24.2)

10 (2)

 

0.001

  1. All tests were two-sided, with a P value of less than 0.05 considered to indicate statistical significance. These results are highlighted in bold
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BMC Gastroenterology

ISSN: 1471-230X

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