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Table 4 Prognosis analysis

From: Immediate postoperative parenteral anticoagulant therapy in patients with mesenteric ischemia after intestinal resection: a retrospective cohort study at a single institute

  

Univariate analysis

Multivariate analysis

  

2-year survival rate (%)

P value

Hazard ratio (95% CI)

P value

Group

A

19.0

0.001

Ref.

0.022

 

B

45.4

 

0.435 (0.213–0.887)

 

Background factors

Age

< 65 years

47.6

0.525

  
 

≥ 65 years

29.9

   

Gender

Female

32.3

0.619

  
 

Male

38.8

   

Type

Non-arterial occlusion

47.5

0.366

  
 

Arterial occlusion

27.5

   

Medical history

Recent cardiovascular procedurea

No

36.6

0.261

  
 

Yes

35.1

   

Coronary artery disease

No

41.1

0.458

  
 

Yes

25.3

   

Cerebral vascular event

No

38.9

0.694

  
 

Yes

20.1

   

Chronic lung disease

No

37.2

0.964

  
 

Yes

25.5

   

Essential hypertension

No

52.4

0.153

  
 

Yes

28.0

 

`

 

Dyslipidemia

No

36.8

0.807

  
 

Yes

22.2

   

Liver cirrhosis

No

35.7

0.787

  
 

Yes

50.0

   

Arterial fibrillation

No

36.1

0.719

  
 

Yes

35.0

   

Diabetes mellitus

No

40.0

0.212

  
 

Yes

28.9

   

Dialysis

No

43.1

0.056

  
 

Yes

19.0

   

Regular antiplatelet or anticoagulant use (n)

No

39.2

0.274

  
 

Yes

30.4

   

Preoperative factors

WBC count out of normal rangeb

No

46.2

0.099

  
 

Yes

28.6

   

Positive band form of WBC

No

63.8

0.000

Ref.

0.301

 

Yes

16.0

 

1.495 (0.698–3.205)

 

NLR

< 23.8

38.2

0.592

  
 

≥ 23.8

30.3

   

Platelet count

≥ 100,000/uL

40.0

0.027

Ref.

0.055

 

< 100,000/uL

26.9

 

2.189 (0.983–4.874)

 

INR of PT

≤ 1.7

40.6

0.000

Ref.

0.012

 

> 1.7

9.1

 

3.006 (1.278–7.071)

 

Hemoglobin

≥ 12 g/dL

46.8

0.151

  
 

< 12 g/dL

28.9

   

Serum albumin

≥ 2.8 g/dL

45.5

0.008

Ref.

0.337

 

< 2.8 g/dL

24.2

 

1.359 (0.727–2.541)

 

Serum ALT

< 100 U/L

39.6

0.002

Ref.

0.858

 

≥ 100 U/L

22.2

 

0.917 (0.354–2.377)

 

Serum bilirubin

< 2.0 mg/dL

39.6

0.049

Ref.

0.437

 

 ≥ 2.0 mg/dL

23.7

 

0.319 (0.656–2.655)

 

Serum creatinine

< 2.0 mg/dL

52.5

0.017

Ref.

0.413

 

≥ 2.0 mg/dL

28.6

 

1.409 (0.620–3.201)

 

Shock status

No

44.9

0.000

Ref.

0.731

 

Yes

18.6

 

1.149 (0.520–2.541)

 

Surgical factors

Time to surgeryc

< 12 h

38.7

0.903

  
 

≥ 12 h

28.7

   

Intraoperative red blood transfusion

No

35.3

0.873

  
 

Yes

38.9

   

Combined colon resection

No

42.7

0.027

Ref.

0.264

 

Yes

19.2

 

1.605 (0.700–3.677)

 

End-enterostomy

No

58.8

0.006

Ref.

0.070

 

Yes

24.5

 

2.525 (0.926–6.880)

 

Functional residual small intestine

≥ 100 cm

45.3

0.019

Ref.

0.802

 

< 100 cm

20.4

 

1.098 (0.528–2.281)

 

Postoperative medical factor

Oral antiplatelets

No

25.5

0.001

Ref.

0.007

 

Yes

61.7

 

0.281 (0.112–0.704)

 
  1. WBC white blood cell; NLR neutrophil-to-lymphocyte ratio; INR international normalized ratio; PT prothrombin time; ALT alanine aminotransferase; CI confidence interval; Ref. reference
  2. aExperiencing major cardiovascular procedure within 90 days before intestine resection
  3. bNormal range of WBC: between 4000 and 12,000/uL
  4. cPeriod between definite diagnosis by contrasted computed tomography and surgery
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BMC Gastroenterology

ISSN: 1471-230X

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