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Table 3 30-day mortality analysis

From: Immediate postoperative parenteral anticoagulant therapy in patients with mesenteric ischemia after intestinal resection: a retrospective cohort study at a single institute

  

Univariate analysis

Multivariate analysis

  

30-days mortality (%)

P value

Odds ratio (95% CI)

P value

Group

A

51.7

0.001

Ref.

0.014

 

B

16.1

 

0.080 (0.011–0.605)

 

Background factors

Age

< 65 years

33.3

0.583

  
 

≥ 65 years

26.6

   

Gender

Female

31.4

0.630

  
 

Male

26.0

   

Type

EAMI

22.2

0.292

  
 

TAMI

25.9

   
 

NOMI

37.1

   
 

VAMI

0.0

   

Medical history

Recent cardiovascular procedurea

No

21.2

0.018

Ref.

0.326

 

Yes

52.6

 

2.765 (0.364–21.028)

 

Coronary artery disease

No

30.8

0.624

  
 

Yes

24.2

   

Cerebral vascular event

No

27.5

0.765

  
 

Yes

31.3

   

Chronic lung disease

No

28.4

1.000

  
 

Yes

27.3

   

Essential hypertension

No

20.8

0.428

  
 

Yes

31.1

   

Dyslipidemia

No

29.1

0.671

  
 

Yes

16.7

   

Liver cirrhosis

No

29.1

0.671

  
 

Yes

16.1

   

Atrial fibrillation

No

27.4

0.733

  
 

Yes

33.3

   

Diabetes mellitus

No

21.6

0.139

  
 

Yes

38.2

   

Dialysis

No

26.6

0.583

  
 

Yes

33.3

   

Regular antiplatelet or anticoagulant use (n)

No

23.1

0.221

  
 

Yes

36.4

   

Preoperative factors

WBC count out of normal rangeb

No

24.3

0.628

  
 

Yes

31.3

   

Positive band form of WBC

No

18.4

0.092

Ref.

0.430

 

Yes

36.2

 

0.487 (0.081–2.912)

 

NLR

< 23.8

27.0

0.784

  
 

≥ 23.8

31.8

   

Platelet count

≥ 100,000/uL

16.9

0.001

Ref.

0.031

 

< 100,000/uL

53.8

 

10.293 (1.231–86.086)

 

INR of PT

≤ 1.7

24.3

0.067

Ref.

0.976

 

> 1.7

54.5

 

0.959 (0.063–14.503)

 

Hemoglobin

≥ 12 g/dL

24.2

0.624

  
 

< 12 g/dL

30.8

   

Serum albumin

≥ 2.8 g/dL

16.7

0.008

Ref.

0.406

 

< 2.8 g/dL

43.2

 

2.003 (0.389–10.314)

 

Serum ALT

< 100 U/L

17.9

0.000

Ref.

0.029

 

≥ 100 U/L

66.7

 

11.523 (1.283–103.481)

 

Serum bilirubin

< 2.0 mg/dL

24.2

0.153

  
 

≥ 2.0 mg/dL

42.1

   

Serum creatinine

< 2.0 mg/dL

11.1

0.020

Ref.

0.716

 

≥ 2.0 mg/dL

36.2

 

1.407 (0.223–8.868)

 

Shock status

No

12.5

0.000

Ref.

0.153

 

Yes

58.6

 

3.438 (0.631–18.723)

 

Surgical factors

Time to surgeryc

< 12 h

30.3

0.567

  
 

≥ 12 h

21.1

   

Intraoperative red blood transfusion

No

28.9

1.000

  
 

Yes

22.2

   

Combined colon resection

No

25.4

0.438

  
 

Yes

34.6

   

End-enterostomy

No

16.0

0.122

  
 

Yes

33.3

   

Functional residual small intestine

≥ 100 cm

22.4

0.224

  
 

< 100 cm

36.1

   

Postoperative medical factor

Oral antiplatelets

No

39.0

0.001

Ref.

0.018

 

Yes

3.8

 

0.025 (0.001–0.528)

 
  1. EAMI arterial embolism; TAMI arterial thrombosis; NOMI non-occlusive mesenteric ischemia; VAMI venous thrombosis; WBC white blood cell; NLR neutrophil-to-lymphocyte ratio; INR international normalized ratio; PT prothrombin time; ALT alanine aminotransferase; CI confidence interval; Ref. reference
  2. aExperiencing major cardiovascular procedure within 90 days before intestine resection
  3. bNormal range of WBC: between 4000 and 12,000/uL
  4. cPeriod between definite diagnosis by contrasted computed tomography and surgery
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BMC Gastroenterology

ISSN: 1471-230X

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