Table 2 Correlation analysis between SLC38A2 and related genes and markers of immune cells in STAD in TIMER.
Description | Gene markers | Purity | None | ||
|---|---|---|---|---|---|
Cor | P | Cor | P | ||
CD8 + T cell | CD8A | -0.22 | 1.54e-05 | 0.128 | 1.27e-02 |
CD8B | -0.121 | 1.82e-02 | 0.042 | 4.12e-01 | |
T cell (general) | CD3D | -0.315 | 3.37e-10 | 0.039 | 4.54e-01 |
CD3E | -0.335 | 2.15e-11 | 0.06 | 2.48e-01 | |
CD2 | -0.303 | 1.72e-09 | 0.121 | 1.80e-02 | |
B cell | CD19 | -0.218 | 1.73e-05 | 0.076 | 1.42e-01 |
CD79A | -0.268 | 1.08e-07 | 0.029 | 5.73e-01 | |
Monocyte | CD86 | -0.286 | 1.45e-08 | 0.195 | 1.36e-04 |
CD115 (CSF1R) | -0.208 | 4.29e-05 | 0.189 | 2.20e-04 | |
TAM | CCL2 | -0.205 | 5.81e-05 | 0.065 | 2.04e-01 |
CD68 | -0.159 | 1.87e-03 | -0.012 | 8.13e-01 | |
IL10 | -0.254 | 5.38e-07 | 0.269 | 1.09e-07 | |
M1 Macrophage | INOS (NOS2) | -0.094 | 6.63e-02 | -0.062 | 2.28e-01 |
IRF5 | -0.111 | 3.03e-02 | 0.11 | 3.25e-02 | |
COX2(PTGS2) | -0.126 | 1.40e-02 | 0.256 | 4.30e-07 | |
M2 Macrophage | CD163 | -0.19 | 1.93e-04 | 0.297 | 3.64e-09 |
VSIG4 | -0.166 | 1.17e-03 | 0.167 | 1.10e-03 | |
MS4A4A | -0.191 | 1.85e-04 | 0.204 | 6.37e-05 | |
Neutrophils | CD66b (CEACAM8) | 0.021 | 6.89e-01 | 0.199 | 9.45e-05 |
CD11b (ITGAM) | -0.164 | 1.34e-03 | 0.183 | 3.36e-04 | |
CCR7 | -0.292 | 6.92e-09 | 0.149 | 3.66e-03 | |
Natural killer cell | KIR2DL1 | -0.077 | 1.37e-01 | 0.197 | 1.09e-04 |
KIR2DL3 | -0.132 | 1.03e-02 | 0.119 | 2.09e-02 | |
KIR2DL4 | -0.165 | 1.25e-03 | 0.149 | 3.55e-03 | |
KIR3DL1 | -0.077 | 1.37e-01 | 0.197 | 1.09e-04 | |
KIR3DL2 | -0.161 | 1.61e-03 | 0.187 | 2.48e-04 | |
KIR3DL3 | -0.02 | 7.73e-01 | 0.089 | 8.34e-02 | |
KIR2DS4 | -0.122 | 1.76e-02 | 0.158 | 2.02e-03 | |
Dendritic cell | HLA-DPB1 | -0.293 | 5.78e-09 | -0.009 | 8.59e-01 |
HLA-DQB1 | -0.282 | 2.11e-08 | -0.002 | 9.76e-01 | |
HLA-DRA | -0.276 | 4.47e-08 | 0.042 | 4.20e-01 | |
HLA-DPA1 | 0.276 | 4.32e-08 | 0.004 | 9.38e-01 | |
BDCA-1(CD1C) | -0.285 | 1.63e-08 | 0.081 | 1.17e-01 | |
BDCA-4(NRP1) | -0.173 | 7.21e-04 | 0.45 | 2.58e-20 | |
CD11c (ITGAX) | -0.224 | 1.03e-05 | 0.231 | 5.34e-06 | |
Th1 | T-bet (TBX21) | -0.254 | 5.25e-07 | 0.138 | 7.21e-03 |
STAT4 | -0.245 | 1.32e-06 | 0.293 | 5.86e-09 | |
STAT1 | -0.104 | 4.20e-02 | 0.292 | 6.80e-09 | |
IFN-γ (IFNG) | -0.19 | 1.99e-04 | 0.125 | 1.47e-02 | |
TNF-α (TNF) | -0.281 | 2.62e-08 | 0.056 | 2.75e-01 | |
Th2 | GATA3 | -0.174 | 6.38e-04 | 0.15 | 3.42e-03 |
STAT6 | 0.011 | 8.36e-01 | 0.238 | 2.81e-06 | |
STAT5A | -0.132 | 1.01e-02 | 0.276 | 4.80e-08 | |
IL13 | -0.002 | 9.71e-01 | -0.031 | 5.43e-01 | |
Tfh | BCL6 | -0.135 | 8.61e-03 | 0.375 | 4.24e-14 |
IL21 | -0.136 | 8.08e-03 | 0.124 | 1.57e-02 | |
Th17 | STAT3 | -0.071 | 1.65e-01 | 0.421 | 1.00e-17 |
IL17A | -0.122 | 1.73e-02 | -0.052 | 3.09e-01 | |
Treg | FOXP3 | -0.241 | 1.94e-06 | 0.084 | 1.01e-01 |
CCR8 | -0.168 | 1.02e-03 | 0.232 | 4.89e-06 | |
STAT5B | -0.023 | 6.61e-01 | 0.352 | 1.70e-12 | |
TGFβ (TGFB1) | -0.169 | 9.50e-04 | 0.234 | 4.11e-06 | |
T cell exhaustion | PD-1 (PDCD1) | -0.175 | 6.21e-04 | 0.096 | 6.24e-02 |
CTLA4 | -0.197 | 1.10e-04 | 0.233 | 4.38e-06 | |
LAG3 | -0.227 | 7.57e-06 | 0.048 | 3.47e-01 | |
TIM-3 (HAVCR2) | -0.245 | 1.35e-06 | 0.197 | 1.18e-04 | |
GZMB | -0.254 | 5.41e-07 | 0.077 | 1.34e-01 | |