Table 1 Prevalent cases, incident cases, years lived with disability (YLD), and years of life lost (YLL) for appendicitis in 2019 for both sexes and percentage change of age-standardized rates (ASR) per 100,000 populations from 1990 to 2019 by Global Burden of Disease regions

Global

672,203

(536,225 to 847,977)

8.7

(6.9 to 11)

20.8

(23 to 18.9)

17,698,765

(14,101,114 to 22,324,572)

229.9

(180.9 to 291)

20.5

(22.8 to 18.7)

211,113

(137,041 to 303,366)

2.7

(1.8 to 3.9)

20.4

(25.1 to 16.2)

Andean Latin America

21,347

(17,402 to 26,573)

32.5

(26.6 to 40.2)

− 30.7

(− 36.6 to − 22.2)

558,662

(456,610 to 696,711)

852.4

(697.7 to 1059.4)

− 30.5

(− 36.6 to − 22)

6569

(4287 to 9596)

10

(6.5 to 14.5)

− 30.7

(− 41.2 to − 17.9)

Australasia

2850

(2247 to 3629)

10.8

(8.4 to 14)

2.4

(− 2.1 to 6.4)

74,147

(58,363 to 94,560)

283.9

(220.1 to 369.3)

2.4

(− 2.1 to 6.4)

882

(546 to 1332)

3.4

(2 to 5.2)

2.4

(− 22.8 to 35.2)

Caribbean

5046

(3913 to 6473)

10.8

(8.3 to 13.9)

28.8

(25.3 to 32)

132,078

(102,639 to 169,890)

282.9

(219.4 to 361.9)

28.6

(25.1 to 31.8)

1574

(1023 to 2353)

3.4

(2.2 to 5)

28.3

(9.7 to 50.4)

Central Asia

8907

(6690 to 11,734)

9.4

(7 to 12.3)

1.5

(− 2 to 5.4)

233,029

(175,238 to 306,969)

245.3

(184.6 to 323.5)

1.5

(− 2.1 to 5.4)

2799

(1767 to 4212)

2.9

(1.8 to 4.4)

1.3

(− 13.5 to 17)

Central Europe

7814

(6451 to 9388)

8.4

(6.7 to 10.4)

7.6

(0.6 to 15.8)

203,543

(167,437 to 245,338)

220.3

(175.2 to 271.3)

7.5

(0.6 to 15.7)

2486

(1625 to 3576)

2.7

(1.7 to 3.9)

7.4

(− 3.7 to 20.2)

Central Latin America

34,366

(26,234 to 44,412)

13.6

(10.3 to 17.6)

16.1

(12.3 to 20.1)

900,312

(686,867 to 1,159,909)

358.2

(271.1 to 460.1)

15.4

(11.8 to 19.4)

10,795

(6781 to 16,177)

4.3

(2.7 to 6.4)

16.3

(6.1 to 27.3)

Central Sub-Saharan Africa

15,752

(11,998 to 20,404)

10.8

(8.5 to 13.8)

36.1

(30.6 to 42.4)

416,895

(315,480 to 538,242)

284.3

(224.9 to 361.7)

35.8

(30.3 to 42.2)

4900

(3015 to 7598)

3.4

(2.1 to 5.1)

36

(8 to 72.8)

East Asia

98,212

(77,893 to 120,704)

6.7

(5.3 to 8.3)

8.4

(2.7 to 14.7)

2,565,267

(2,034,140 to 3,149,307)

176.2

(138.5 to 220)

7.4

(1.8 to 13.6)

31,567

(20,685 to 45,211)

2.2

(1.4 to 3.1)

9.1

(1.5 to 18.2)

Eastern Europe

18,435

(14,229 to 23,497)

10.4

(7.8 to 13.6)

19.9

(17.3 to 22.8)

480,413

(370,619 to 612,175)

273.2

(202.6 to 354.6)

19.7

(17.1 to 22.5)

5795

(3710 to 8441)

3.3

(2.1 to 4.9)

19.7

(9.4 to 31.6)

Eastern Sub-Saharan Africa

22,041

(16,104 to 29,956)

4.7

(3.6 to 6.3)

46.5

(42.9 to 49.9)

591,822

(432,475 to 797,031)

127

(96.7 to 166.9)

45.7

(42.2 to 49)

6956

(4286 to 10,506)

1.5

(0.9 to 2.2)

45.5

(31.2 to 61.2)

High-income Asia Pacific

22,677

(17,978 to 28,337)

17.2

(13.1 to 22.1)

− 2.6

(− 7.2 to 2.3)

586,290

(463,318 to 730,184)

448.1

(339.7 to 572.3)

− 2.6

(− 7.2 to 2.5)

7111

(4538 to 10,230)

5.4

(3.4 to 7.9)

− 2.2

(− 11.7 to 8.9)

High-income North America

21,877

(19,671 to 24,295)

6.2

(5.5 to 6.9)

− 10.4

(− 21.8 to 4)

571,783

(514,543 to 636,513)

162.6

(144.9 to 182.1)

− 10.3

(− 21.7 to 4.1)

7057

(4756 to 9721)

2

(1.3 to 2.8)

− 8.9

(− 21.9 to 6.8)

North Africa and Middle East

66,665

(50,979 to 87,066)

10.4

(8 to 13.5)

48.2

(44.1 to 52.5)

1,745,503

(1,329,173 to 2,271,525)

271.6

(206.1 to 350.9)

48

(43.9 to 52.2)

20,714

(12,951 to 30,887)

3.2

(2 to 4.8)

46.5

(32.5 to 63)

Oceania

577

(444 to 755)

4.1

(3.2 to 5.4)

16.2

(12.2 to 21.1)

15,219

(11,665 to 19,748)

109.2

(85 to 140.3)

16.1

(12.1 to 21)

187

(118 to 279)

1.3

(0.9 to 2)

16.2

(12.2 to 21.1)

South Asia

196,227

(154,672 to 249,562)

10

(8 to 12.6)

53.5

(45.9 to 61)

5,214,009

(4,114,157 to 6,620,999)

266.7

(212.7 to 334.9)

51.8

(44.3 to 59.1)

60,854

(38,899 to 89,567)

3.1

(2 to 4.5)

52.5

(36.3 to 70.7)

Southeast Asia

43,365

(33,776 to 56,231)

6.3

(4.9 to 8.1)

34.2

(30.6 to 37.7)

1,146,656

(892,434 to 1,477,241)

166.5

(129.2 to 216.3)

33.9

(30.4 to 37.4)

13,780

(8689 to 20,227)

2

(1.3 to 2.9)

34.5

(20.4 to 51.4)

Southern Latin America

7736

(6046 to 9784)

11.7

(9 to 14.9)

49.8

(42 to 57.6)

201,955

(157,808 to 254,876)

305.5

(236.3 to 389.3)

49.6

(41.8 to 57.5)

2394

(1497 to 3585)

3.6

(2.2 to 5.4)

46.6

(14.1 to 86.4)

Southern Sub-Saharan Africa

5855

(4394 to 7749)

6.9

(5.2 to 9.1)

26.2

(22.4 to 30.6)

154,821

(116,584 to 203,979)

183

(138.5 to 241)

25.9

(22.1 to 30.2)

1837

(1152 to 2840)

2.2

(1.4 to 3.3)

25.1

(10 to 43.7)

Tropical Latin America

11,326

(9235 to 14,000)

5.1

(4.1 to 6.3)

28.9

(23.6 to 35.5)

298,011

(243,250 to 366,750)

135.6

(109.7 to 167.8)

27.8

(22.6 to 34.3)

3616

(2379 to 5269)

1.6

(1.1 to 2.4)

27.8

(17.7 to 39.9)

Western Europe

38,356

(31,229 to 47,142)

10.6

(8.5 to 13.6)

12.1

(6.6 to 18.3)

997,135

(806,633 to 1,229,567)

278.5

(220.2 to 352.8)

12.1

(6.6 to 18.3)

11,990

(7743 to 17,155)

3.3

(2.1 to 4.8)

12

(0.6 to 25.9)

Western Sub-Saharan Africa

22,773

(16,551 to 30,697)

4.5

(3.4 to 6)

48.7

(43.6 to 54)

611,213

(445,004 to 824,269)

120.1

(89.7 to 158.9)

47.6

(42.4 to 52.8)

7249

(4465 to 11,015)

1.4

(0.9 to 2.2)

47.9

(37 to 58.6)