Table 3 Adverse events following regorafenib therapy
Any grade, Number (%) | Grade ≥ 3, Number (%) | |
|---|---|---|
Hand-foot skin reaction | 22 (23.7%) | 0 |
Weakness | 17 (18.3%) | 1 (1.1%) |
Skin rash | 16 (17.2%) | 2 (2.2%) |
Diarrhea | 7 (7.5%) | 0 |
Hypertension | 7 (7.5%) | 0 |
Mucositis | 5 (5.3%) | 0 |
Anorexia | 3 (3.2%) | 1 (1.1%) |
Proteinuria | 3 (3.2%) | 0 |
Renal dysfunction | 3 (3.2%) | 2 (2.2%) |
Hepatocyte dysfunction | 2 (2.2%) | 2 (2.2%) |
Headache | 1 (1.1%) | 1 (1.1%) |
Myelosuppression | 1 (1.1%) | 1 (1.1%) |