Skip to main content

Table 1 Association between preoperative CA125 level and clinicopathological parameters

From: Prognostic significance of serum CA125 in the overall management for patients with gastrointestinal stromal tumors

 

Normal CA125 level (n = 360)

High CA125 level (n = 46)

P value

Agea

59.00 (51.00,67.00)

57.50 (51.25,68.00)

0.887

Gender (%)

  

0.056

 Male

181 (50.3)

30 (65.2)

 

 Female

179 (49.7)

16 (34.8)

 

Hemorrhage (%)

  

0.868

 Yes

106 (29.4)

13 (28.3)

 

 No

254 (70.6)

33 (71.7)

 

Rupture (%)

  

< 0.001

 Yes

1 (0.3)

8 (17.4)

 

 No

359 (99.7)

38 (82.6)

 

Resection style (%)

  

0.001

 Complete resection

348 (96.7)

38 (82.6)

 

 Incomplete resection

12 (3.3)

8 (17.4)

 

Tumor site (%)

  

0.025

 Stomach

241 (66.9)

23 (50.0)

 

 Small intestine

103 (28.6)

17 (37.0)

 

 Colorectum

7 (1.9)

2 (4.3)

 

 Extra location

9 (2.5)

4 (8.7)

 

Tumor size (%)

  

 < 0.001

 Less than 5 cm

197 (54.7)

5 (10.9)

 

 5–10 cm

138 (38.3)

19 (41.3)

 

 More than 10 cm

25 (6.9)

22 (47.8)

 

Mitotic index (%)

  

< 0.001

 Less than 5/HPF

243 (67.5)

18 (39.1)

 

 5–10/HPF

55 (15.3)

6 (13.0)

 

 More than 10/HPF

62 (17.2)

22 (47.8)

 

NIH risk grade (%)

  

 < 0.001

 Extremely low

25 (6.9)

0 (0.0)

 

 Low

135 (37.5)

3 (6.5)

 

 Moderate

69 (19.2)

2 (4.3)

 

 High

131 (36.4)

41 (89.1)

 

c-kit exons (%)

  

0.001

 Positive

138 (38.3)

29 (63.0)

 

 Negative

222 (61.7)

17 (37.0)

 

PDGFRA exons (%)

  

0.113

 Positive

22 (6.1)

6 (13.0)

 

 Negative

338 (93.9)

40 (87.0)

 
  1. Bold indicates statistically significant (P < 0.05)
  2. aMedian (P25, P75)