Table 1 Basal clinical parameters of patients with or without development of NAFLD at follow-up
Variables | Male | Female | ||||
|---|---|---|---|---|---|---|
NAFLD state at follow-up | P-value | NAFLD state at follow-up | P-value | |||
Non-NAFLD n = 160 | NAFLD n = 55 | Non-NAFLD n = 123 | NAFLD n = 17 | |||
Age (year) | 58 (50, 66) | 53 (45, 60) | 0.003 | 56 (45, 65) | 53 (49, 61) | 0.385 |
BMI (kg/m2) | 23.84 (22.05, 25.40) | 24.22 (22.35, 26.23) | 0.241 | 23.75 (20.45, 26.59) | 26.56 (23.46, 29.40) | 0.067 |
WC (cm) | 90 (85, 95) | 93 (86, 98) | 0.174 | 83 (78, 96) | 91 (79, 99) | 0.294 |
Follow-up (month) | 32 (21, 45) | 34 (22, 50) | 0.333 | 30 (14, 43) | 34 (14, 50) | 0.540 |
Diabetes, n (%) | 158 (98.8%) | 50 (90.9%) | 0.005 | 94 (76.4%) | 14 (82.4%) | 0.585 |
Hypertension, n (%) | 83 (51.9%) | 31 (56.4%) | 0.565 | 65 (52.8%) | 7 (41.2%) | 0.367 |
Hyperlipidemia, n (%) | 40 (25.0%) | 23 (41.8%) | 0.018 | 31 (25.2%) | 7 (41.2%) | 0.165 |
SBP (mmHg) | 133 (120, 144) | 130 (118, 139) | 0.129 | 133 (121, 148) | 126 (104, 149) | 0.191 |
DBP (mmHg) | 78 (71, 86) | 78 (71, 89) | 0.462 | 78 (69, 86) | 70 (63, 91) | 0.368 |
HbA1c (%) | 7.90 (6.75, 10.00) | 7.60 (6.30, 10.90) | 0.297 | 7.05 (6.00, 9.23) | 8.50 (5.50, 10.90) | 0.559 |
FBG (mmol/L) | 7.08 (5.58, 8.94) | 6.97 (5.47, 8.85) | 0.932 | 5.98 (4.89, 8.39) | 6.44 (4.68, 10.60) | 0.753 |
HOMA-IR | 1.47 (0.81, 3.00) | 2.04 (1.42, 3.20) | 0.032 | 1.84 (1.01, 3.97) | 1.79 (1.21, 3.98) | 0.925 |
TG (mmol/L) | 1.07 (0.77, 1.50) | 1.53 (1.03, 2.04) | 0.001 | 1.03 (0.68, 1.42) | 1.25 (0.85, 1.90) | 0.084 |
TC (mmol/L) | 4.04 (3.56, 4.80) | 4.45 (3.59, 5.48) | 0.019 | 4.43 (3.76, 5.22) | 4.46 (4.15, 5.46) | 0.515 |
HDL-C (mmol/L) | 1.07 (0.84, 1.28) | 0.97 (0.84, 1.21) | 0.240 | 1.19 (0.98, 1.57) | 1.15 (1.05, 1.37) | 0.506 |
LDL-C (mmol/L) | 2.30 (1.78, 2.80) | 2.55 (1.77, 3.21) | 0.086 | 2.47 (1.98, 3.04) | 2.77 (2.26, 3.38) | 0.258 |
ALT (U/L) | 17.60 (13.85, 24.23) | 17.40 (14.05, 28.00) | 0.347 | 17.80 (13.70, 24.80) | 23.90 (13.50, 33.25) | 0.415 |
AST (U/L) | 17.20 (14.90, 20.50) | 18.60 (14.15, 22.05) | 0.872 | 18.90 (15.70, 22.10) | 17.80 (14.50, 23.85) | 0.790 |
Cr (umol/L) | 66.00 (60.00, 76.00) | 65.00 (58.50, 74.00) | 0.250 | 50.00 (43.00, 57.20) | 48.00 (40.50, 57.50) | 0.607 |
UA (umol/L) | 318.50 (267.25, 372.00) | 328.00 (287.50, 412.50) | 0.050 | 270.00 (226.50, 312.75) | 290.00 (247.00, 331.50) | 0.544 |
eGFR (ml/min/1.73 m2) | 116.46 (100.05, 130.16) | 116.30 (99.24, 140.18) | 0.596 | 116.69 (103.09, 142.47) | 130.61 (100.99, 168.35) | 0.427 |
TSH (mIU/L) | 1.78 (1.34, 2.60) | 1.83 (1.13, 2.63) | 0.904 | 2.20 (1.44, 3.19) | 1.98 (1.45, 3.22) | 0.878 |
PRL (ug/L) | 9.13 (6.92, 12.50) | 7.35 (5.48, 10.60) | 0.002 | 9.01 (6.31, 11.60) | 5.66 (4.67, 9.03) | 0.009 |