Table 2 Characteristics of the patients with MAFLD according to their TSH levels, n = 5495
|  | Strict-normal N = 4056 | Low thyroid function N = 1439 | P Value | Low thyroid function (TSH ≥ 2.5 mIU/L) | ||
|---|---|---|---|---|---|---|
Low-normal N = 1207 | SCH N = 232 | P Value | ||||
Age | 49.69 ± 15.46 | 54.84 ± 16.56 |  < 2.2e−16 | 54.02 ± 16.39 | 59.06 ± 16.82 | 3.48e−05 |
Male, % | 75.62 | 57.09 |  < 2.2e−16 | 58.04 | 52.16 | 0.113 |
BMI | 26.33 ± 2.81 | 26.33 ± 2.94 | 0.123 | 26.18 ± 2.97 | 26.18 ± 2.79 | 0.370 |
T2DM, % | 12.52 | 15.08 | 0.016 | 14.17 | 19.83 | 0.035 |
Hypertension, % | 46.91 | 52.97 | 9.36e−05 | 52.91 | 53.25 | 0.983 |
Total cholesterol | 5.03 ± 0.95 | 5.07 ± 1.00 | 0.152 | 5.07 ± 0.99 | 5.07 ± 1.09 | 0.947 |
HDL cholesterol | 1.12 ± 0.23 | 1.15 ± 0.26 | 2.35e−04 | 1.15 ± 0.26 | 1.16 ± 0.25 | 0.579 |
LDL cholesterol | 3.15 ± 0.85 | 3.15 ± 0.89 | 0.912 | 3.14 ± 0.87 | 3.21 ± 0.97 | 0.273 |
Triglycerides | 2.37 ± 1.67 | 2.46 ± 1.82 | 0.107 | 2.50 ± 1.92 | 2.24 ± 1.17 | 0.006 |
ALT, U/L | 37.17 ± 27.42 | 34.13 ± 28.29 | 4.28e-04 | 34.40 ± 29.33 | 32.76 ± 22.07 | 0.329 |
AST, U/L | 25.67 ± 13.06 | 25.55 ± 13.59 | 0.785 | 25.58 ± 14.08 | 25.43 ± 10.69 | 0.857 |
GGT, U/L | 47.04 ± 40.94 | 43.30 ± 42.97 | 0.004 | 43.82 ± 44.62 | 40.60 ± 33.01 | 0.202 |
ALP, U/L | 73.44 ± 19.17 | 72.73 ± 20.02 | 0.241 | 72.88 ± 19.72 | 71.93 ± 21.57 | 0.532 |
Glucose, mmol/L | 5.75 ± 1.70 | 5.88 ± 1.75 | 0.019 | 5.83 ± 1.69 | 6.13 ± 2.01 | 0.032 |
Platelet, 109/L | 221.73 ± 55.35 | 221.22 ± 61.25 | 0.781 | 222.21 ± 61.91 | 216.05 ± 57.52 | 0.141 |
Albumin, g/L | 46.63 ± 2.53 | 46.36 ± 2.65 | 0.001 | 46.38 ± 2.68 | 46.30 ± 2.50 | 0.675 |
FIB-4 > 1.30, % | 29.58 | 40.21 | 1.87e−13 | 37.91 | 52.16 | 6.89e−05 |
FIB-4 > 2.67, % | 3.39 | 6.48 | 7.54e−07 | 6.40 | 6.90 | 0.892 |
NFS > − 1.455, % | 25.09 | 33.66 | 4.79e−10 | 32.09 | 41.81 | 0.005 |
NFS > 0.676, % | 1.63 | 3.41 | 8.06e−05 | 3.49 | 3.02 | 0.868 |