Table 1 Characteristics of the study participants according to their TSH levels, n = 19,946
Variables | Strict-normal thyroid (n = 14,789) | Low thyroid function (n = 5,157) | P Value | Low thyroid function (n = 5,157) | ||
|---|---|---|---|---|---|---|
Low-normal (n = 4,328) | SCH (n = 829) | P Value | ||||
Age, year | 46.10 ± 15.69 | 50.78 ± 17.71 | 3.35e−62 | 49.84 ± 17.34 | 55.67 ± 18.75 | 3.23e−16 |
Male, % | 56.17 | 43.03 | 2.49e−59 | 43.40 | 41.13 | 0.243 |
BMI, kg/m2 | 23.50 ± 3.32 | 23.50 ± 3.31 | 0.978 | 23.49 ± 3.34 | 23.49 ± 3.17 | 0.933 |
T2DM, % | 5.74 | 7.24 | 1.26e−04 | 6.77 | 9.66 | 0.004 |
Hypertension, % | 28.52 | 34.90 | 1.12e−17 | 34.18 | 38.67 | 0.015 |
Total cholesterol | 4.81 ± 0.91 | 4.87 ± 0.97 | 8.88e−05 | 4.87 ± 0.96 | 4.92 ± 1.04 | 0.191 |
HDL cholesterol | 1.32 ± 0.33 | 1.34 ± 0.34 | 5.97e−05 | 1.34 ± 0.34 | 1.33 ± 0.34 | 0.780 |
LDL cholesterol | 2.97 ± 0.81 | 3.00 ± 0.85 | 0.040 | 2.99 ± 0.84 | 3.03 ± 0.91 | 0.287 |
Triglycerides | 1.58 ± 1.23 | 1.67 ± 1.40 | 1.78e−04 | 1.66 ± 1.43 | 1.69 ± 1.22 | 0.545 |
ALT, U/L | 23.67 ± 20.18 | 22.51 ± 20.25 | 4.02e−04 | 22.58 ± 20.75 | 22.16 ± 17.40 | 0.543 |
AST, U/L | 20.97 ± 9.97 | 21.37 ± 10.14 | 0.0149 | 21.24 ± 10.25 | 22.03 ± 9.54 | 0.032 |
GGT, U/L | 31.09 ± 31.39 | 29.32 ± 32.85 | 7.57e−04 | 29.25 ± 33.31 | 29.70 ± 30.39 | 0.701 |
ALP, U/L | 67.81 ± 19.35 | 68.03 ± 22.30 | 0.523 | 67.48 ± 21.40 | 70.90 ± 26.36 | 4.50e−04 |
Glucose, mmol/L | 5.27 ± 1.26 | 5.36 ± 1.31 | 1.26e−05 | 5.33 ± 1.27 | 5.52 ± 1.51 | 4.58e−04 |
Platelets 109/L | 218.81 ± 55.27 | 216.86 ± 59.63 | 0.039 | 218.00 ± 59.15 | 210.90 ± 61.78 | 0.002 |
Albumin, g/L | 46.26 ± 2.57 | 46.07 ± 2.73 | 9.46e−06 | 46.12 ± 2.69 | 45.80 ± 2.92 | 0.003 |
MAFLD, % | 27.43 | 27.90 | 0.520 | 27.89 | 27.99 | 0.988 |