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Table 1 Participant characteristics of GC cases and controls according to sex

From: Sex-dependent associations between MAP3K1 gene polymorphisms and soy products with the gastric cancer risk in Korea: a case-control study

Characteristics

Men (n=328)

Women (n=164)

Cases (n=164)

Controls (n=164)

p-values

Cases (n=82)

Controls (n=82)

p-values

Age (y, mean ± SD)

57.8

± 10.8

56.7

±11.0

0.353

55.9

±13.7

56.1

±12.9

0.916

Education level (n, %)

 ≤ Middle school

66

(40.2)

61

(37.2)

0.802

45

(54.9)

45

(54.9)

0.959

 ≥ High school

82

(50.0)

88

(53.7)

 

29

(35.4)

30

(36.6)

 

Missing

16

(9.8)

15

(9.1)

 

8

(9.7)

7

(8.5)

 

Smoking status (n, %)

 Never

16

(9.8)

30

(18.3)

0.026

70

(85.4)

76

(92.7)

0.134

 Former & Current

148

(90.2)

134

(81.7)

 

12

(14.6)

6

(7.3)

 

Alcohol consumption (n, %)

 Never

28

(17.1)

27

(16.5)

0.883

56

(68.3)

56

(68.3)

1.000

 Former & Current

136

(82.9)

137

(83.5)

 

26

(31.7)

26

(31.7)

 

Body mass index (kg/m2) (n, %)

 ≤ 22.99

82

(50.0)

56

(34.2)

0.014

45

(54.8)

32

(39.0)

0.122

 ≥ 23.0

74

(45.1)

99

(60.4)

 

29

(35.4)

38

(46.4)

 

 Missing

8

(4.9)

9

(5.5)

 

8

(9.8)

12

(14.6)

 

Hospital (n, %)

 Chungnam university

58

(35.4)

58

(35.4)

1.000

28

(34.2)

28

(34.2)

1.000

 Hanyang university Guri

106

(64.6)

106

(64.6)

 

54

(65.8)

54

(65.8)

 

Family history of gastric cancer (n, %)a

 No

138

(84.1)

148

(90.2)

0.098

72

(87.8)

74

(90.2)

0.617

 Yes

26

(15.9)

16

(9.8)

 

10

(12.2)

8

(9.8)

 

H. pylori infection (n, %)

 No

58

(35.4)

43

(26.2)

0.009

29

(35.4)

13

(15.9)

0.017

 Yes

52

(31.7)

79

(48.2)

 

24

(29.2)

31

(37.8)

 

 Undetermined

54

(32.9)

42

(25.6)

 

29

(35.4)

38

(46.3)

 

MAP3K1 rs252902 polymorphisms (n, %)

 GG

45

(27.4)

73

(44.5)

0.004

33

(40.3)

28

(34.2)

0.529

 GA

81

(49.4)

67

(40.9)

 

37

(45.1)

37

(45.1)

 

 AA

38

(23.2)

24

(14.6)

 

12

(14.6)

17

(20.7)

 

Daily intake of dietary factor (mean ± SD)

 Total energy intake (kcal/d)

2011

±760

1770

±644

0.002

1509

±516

1593

±485

0.285

 Noodle and dumpling (g/day)

92.2

±137.8

60.1

±64.5

0.008

44.6

±43.4

43.2

±47.9

0.841

 Soy products (g/day)

19.3

±35.3

16.6

±30.6

0.464

22.1

±72.4

16.3

±33.8

0.508

  1. afirst-degree relatives. Based on Student’s t-test for continuous variables, or chi-squared test for categorical variables